Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 10/20 | 0.76 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.76 |
| ▸ | HTR2C | P28335 | 4/20 | 0.66 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.65 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.65 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | HTR1D | P28221 | 5/20 | 0.59 |
| ▸ | HTR1B | P28222 | 3/20 | 0.59 |
| ▸ | MPO | P05164 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | HTR6 | P50406 | 2/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | CTSK | P43235 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32684044 | 1.00 | HTR2A (0.76) | HTR2ATRPM8HTR2CCHRNB2CHRNA7 | |
| Hydrochloric Acid SCHEMBL2706928 | 0.98 | HTR2A (0.73) | HTR2ATRPM8HTR2CCHRNB2CHRNA7 | |
| Cyanide SCHEMBL29233342 | 0.95 | HTR2A (0.69) | HTR2ATRPM8HTR2CCHRNB2CHRNA7 | |
| SCHEMBL29791683 | 0.86 | HTR2A (1.00) | HTR2ATRPM8HTR2CKMT2AMEN1 | |
| SCHEMBL1520598 | 0.86 | HTR2A (1.00) | HTR2ATRPM8HTR2CKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL31109110 | 0.85 | HTR2A (0.97) | HTR2ATRPM8HTR2CKMT2AHTR1D | |
| Hydrochloric Acid SCHEMBL687689 | 0.85 | HTR2A (0.97) | HTR2ATRPM8HTR2CKMT2AHTR1D | |
| Methane SCHEMBL21333446 | 0.85 | HTR2A (0.97) | HTR2ATRPM8HTR2CKMT2AMEN1 | |
| SCHEMBL4227663 | 0.83 | CHRNB2 (0.65) | HTR2ATRPM8HTR2CCHRNB2CHRNA7 | |
| Cyanide SCHEMBL28693742 | 0.82 | HTR2A (0.91) | HTR2ATRPM8HTR2CKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850269-A | Tetrahydro-beta-carboline compound and preparation method and application thereof | 南京工业大学 | 2023-03-28 | — | — | CN | claimed |
| CN-107118146-A | A kind of 6 bromine tryptamine derivatives and its production and use | 宁波大学 | 2017-09-01 | — | — | CN | claimed |
| US-9511378-B2 | Collector compositions and methods for making and using same | GEORGIA-PACIFIC CHEMICALS LLC (US) | 2016-12-06 | — | — | US | claimed |
| US-12559486-B2 | Tau-protein targeting compounds and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2026-02-24 | — | — | US | disclosed |
| US-20250354108-A1 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | UNIV DANMARKS TEKNISKE (DK) | 2025-11-20 | — | — | US | disclosed |
| CN-119954801-A | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-05-09 | — | — | CN | disclosed |
| CN-114867727-B | TAU protein targeting compounds and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-02-21 | — | — | CN | disclosed |
| US-20240217962-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. | 2024-07-04 | — | — | US | disclosed |
| US-11912699-B2 | Tau-protein targeting compounds and associated | ARVINAS OPERATIONS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-11912699-B2 | Tau-protein targeting compounds and associated | ARVINAS OPERATIONS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-11912699-B2 | Tau-protein targeting compounds and associated | ARVINAS OPERATIONS, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| US-20070099909-A1 | N-(2-ARYLETHYL)BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | CHEN ZHAOGEN | 2007-05-03 | — | — | US | disclosed |
| US-7157488-B2 | N-(2-Arylethyl) benzylamines as antagonists of the 5-HT6 receptor | ELI LILLY AND COMPANY (US) | 2007-01-02 | — | — | US | disclosed |
| US-20060009511-A9 | N-(2-arylethyl) benzylamines as antagonists of the 5-ht6 receptor | CHEN ZHAOGEN | 2006-01-12 | — | — | US | disclosed |
| CN-1610547-A | N-(2-arylethyl)benzylamines as antagonists of the 5-HT6 receptor | LILLY CO ELI (US) | 2005-04-27 | — | — | CN | disclosed |
| EP-1379239-A2 | N-(2-ARYLETHYL) BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | ELI LILLY AND COMPANY (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2002078693-A2 | N-(2-ARYLETHYL)BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | ELI LILLY AND COMPANY (US) | 2002-10-10 | — | — | WO | disclosed |
| EP-0273321-B1 | 7-BROMO-BETA-CARBOLINE COMPOUND AND METHOD FOR PRODUCING SAME | Kawaken Fine Chemicals Co., Ltd. (JP) | 1992-04-22 | — | — | EP | disclosed |
| US-4894457-A | BROMINATION, HYDROLYSIS | KAWAKEN FINE CHEMICALS CO., LTD. (JP) | 1990-01-16 | — | — | US | disclosed |
| EP-0273321-A1 | 7-Bromo-beta-carboline compound and method for producing same | Kawaken Fine Chemicals Co., Ltd. (JP) | 1988-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912699-B2 | Tau-protein targeting compounds and associated | MAPT, VHL, CRBN | HTR2A 3221/4885TRPM8 4185/4885HTR2C 3471/4885 |
| US-20060009511-A9 | N-(2-arylethyl) benzylamines as antagonists of the 5-ht6 receptor | HTR6, HTR2C, HTR1B | HTR2A 5/4885TRPM8 511/4885HTR2C 2/4885 |
| US-20240217962-A1 | TAU-PROTEIN TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | VHL, CRBN, MAPT | HTR2A 3396/4885TRPM8 4362/4885HTR2C 3542/4885 |
| US-12559486-B2 | Tau-protein targeting compounds and associated methods of use | UBQLN2, UBQLN1, CRBN | HTR2A 3355/4885TRPM8 3385/4885HTR2C 2447/4885 |
| US-20070099909-A1 | N-(2-ARYLETHYL)BENZYLAMINES AS ANTAGONISTS OF THE 5-HT6 RECEPTOR | HTR6, HTR2C, HTR1B | HTR2A 5/4885TRPM8 511/4885HTR2C 2/4885 |
| US-20250354108-A1 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | INMT, KARS1, MIA3 | HTR2A 2339/4885TRPM8 3824/4885HTR2C 2595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.