Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | MYC | P01106 | 2/20 | 0.36 |
| ▸ | GSTP1 | P09211 | 3/20 | 0.36 |
| ▸ | GSTM2 | P28161 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25342625 | 0.82 | KCNH2 (0.36) | KCNH2MEN1KMT2AIDO1TDO2 | |
| SCHEMBL25342264 | 0.79 | IDO1 (0.47) | KCNH2MEN1KMT2AIDO1TDO2 | |
| SCHEMBL25343517 | 0.77 | IDO1 (0.49) | KCNH2MEN1KMT2AIDO1TDO2 | |
| SCHEMBL31054006 | 0.75 | GSTP1 (0.53) | KCNH2MEN1KMT2AIDO1TDO2 | |
| SCHEMBL25342570 | 0.73 | MEN1 (0.44) | KCNH2MEN1KMT2AIDO1TDO2 | |
| SCHEMBL31054036 | 0.71 | MYC (0.40) | KCNH2MYCGSTP1GSTM2ALDH1A1 | |
| SCHEMBL25429997 | 0.71 | MYC (0.40) | KCNH2MYCGSTP1GSTM2ALDH1A1 | |
| SCHEMBL4439764 | 0.71 | MEN1 (0.54) | KCNH2MEN1KMT2AIDO1GSTP1 | |
| SCHEMBL30521247 | 0.69 | IDO1 (0.49) | KCNH2MEN1KMT2AIDO1TDO2 | |
| SCHEMBL25341098 | 0.66 | POLB (0.47) | MEN1KMT2AIDO1TDO2MYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023143494-A1 | NEW PROTAC COMPOUND | 甘李药业股份有限公司 | 2023-08-03 | — | — | WO | disclosed |