SCHEMBL2535426

SCHEMBL2535426

N=C(N)c1ccc(OCCC(CCCOc2ccccc2)C(=N)N)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 8/20 0.59
TMPRSS2 O15393 2/20 0.59
PRMT1 Q99873 3/20 0.58
F2 P00734 3/20 0.58
ST14 Q9Y5Y6 2/20 0.58
PLG P00747 2/20 0.58
PLAU P00749 1/20 0.58
PRMT5 O14744 1/20 0.58
SLC22A2 O15244 1/20 0.58
SLC22A1 O15245 1/20 0.58
PTP4A3 O75365 1/20 0.58
SLC22A3 O75751 1/20 0.58
F10 P00742 1/20 0.58
S100B P04271 1/20 0.58
CHRM2 P08172 1/20 0.58
CHRM4 P08173 1/20 0.58
CHRM5 P08912 1/20 0.58
ADRA2A P08913 1/20 0.58
CYP2D6 P10635 1/20 0.58
AOC1 P19801 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5197177 0.88 ALDH1A1 (0.67) PRSS1TMPRSS2PRMT1F2ST14
SCHEMBL1820546 0.82 PRMT1 (0.86) PRSS1TMPRSS2PRMT1F2ST14
SCHEMBL6408670 0.77 PRSS1 (1.00) PRSS1TMPRSS2PRMT1F2ST14
Propamidine SCHEMBL231060 0.77 TMPRSS2 (1.00) PRSS1TMPRSS2PRMT1F2ST14
SCHEMBL12348099 0.76 PRSS1 (0.72) PRSS1TMPRSS2PRMT1F2ST14
SCHEMBL15339481 0.75 PRSS1 (0.66) PRSS1TMPRSS2PRMT1F2ST14
Pentamidine SCHEMBL3329 0.75 PRMT1 (1.00) PRSS1TMPRSS2PRMT1F2ST14
Hexamidine SCHEMBL144738 0.75 PRMT1 (1.00) PRSS1TMPRSS2PRMT1F2ST14
Heptamidine SCHEMBL14599630 0.75 PRMT1 (1.00) PRSS1TMPRSS2PRMT1F2ST14
SCHEMBL14599639 0.75 PRMT1 (1.00) PRSS1TMPRSS2PRMT1F2ST14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1131044-A1 SKIN DEODORIZING AND SANITIZING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2001-09-12 EP claimed
WO-2000030599-A1 SKIN DEODORIZING AND SANITIZING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2000-06-02 WO claimed
US-20240115437-A1 ABSORBENT ARTICLE COMPRISING A FRAGRANCE AND AN ODOR CONTROL COMPOSITION THE PROCTER & GAMBLE COMPANY 2024-04-11 US disclosed
US-10568781-B2 Sanitary napkins capable of taking complex three-dimensional shape in use THE PROCTER & GAMBLE COMPANY (US) 2020-02-25 US disclosed
US-10265434-B2 Absorbent articles comprising glyceride copolymers THE PROCTER & GAMBLE COMPANY (US) 2019-04-23 US disclosed
US-20180161474-A1 ABSORBENT ARTICLES COMPRISING GLYCERIDE COPOLYMERS THE PROCTER & GAMBLE COMPANY 2018-06-14 US disclosed
US-20180008484-A1 ABSORBENT ARTICLES COMPRISING METATHESIZED UNSATURATED POLYOL ESTERS THE PROCTER & GAMBLE COMPANY 2018-01-11 US disclosed
EP-2372017-B1 SOFTENER COMPOSITION KAO CORP (JP) 2017-09-13 EP disclosed
US-20170119591-A1 SANITARY NAPKINS CAPABLE OF TAKING COMPLEX THREE-DIMENSIONAL SHAPE IN USE PROCTER & GAMBLE (US) 2017-05-04 US disclosed
EP-1922090-B1 SANITARY NAPKINS WITH HYDROPHOBIC LOTIONS PROCTER & GAMBLE (US) 2016-03-30 EP disclosed
US-20150073367-A1 SANITARY NAPKINS WITH HYDROPHOBIC LOTIONS PROCTER & GAMBLE (US) 2015-03-12 US disclosed
WO-1996004939-A1 FABRIC TREATING COMPOSITION CONTAINING BETA-CYCLODEXTRIN THE PROCTER & GAMBLE COMPANY (US) 1996-02-22 WO disclosed
WO-1996004938-A1 COMPOSITION FOR REDUCING MALODOR IMPRESSION ON INANIMATE SURFACES THE PROCTER & GAMBLE COMPANY (US) 1996-02-22 WO disclosed
WO-1996005358-A1 UNCOMPLEXED CYCLODEXTRIN SOLUTIONS FOR ODOR CONTROL ON INANIMATE SURFACES THE PROCTER & GAMBLE COMPANY (US) 1996-02-22 WO disclosed
EP-0579729-A1 QUATERNARY AMMONIUM ANTIBACTERIAL DENTIFRICES WITH SELECTED CALCIUM ABRASIVES SMITHKLINE BEECHAM CORPORATION (US) 1994-01-26 EP disclosed
US-5176901-A Cationic Quaternary Ammonium Bactericides SMITHKLINE BEECHAM CORPORATION (US) 1993-01-05 US disclosed
WO-1992018096-A1 QUATERNARY AMMONIUM ANTIBACTERIAL DENTIFRICES WITH SELECTED CALCIUM ABRASIVES SMITHKLINE BEECHAM CORPORATION (US) 1992-10-29 WO disclosed
US-4357476-A Nonylamines CIBA GEIGY CORPORATION, N.Y. (US) 1982-11-02 US disclosed
US-4139560-A Nonylamines CIBA GEIGY CORPORATION (US) 1979-02-13 US disclosed
US-3991124-A FOR CONTROLLING MICROORGANISMS AND HELMINTHS CIBA-GEIGY CORPORATION (US) 1976-11-09 US disclosed