Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | MARS1 | P56192 | 4/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4513922 | 0.89 | CNR1 (0.38) | CNR1DPP4 | |
| SCHEMBL2536778 | 0.79 | CNR1 (0.48) | CNR1MARS1SRD5A2 | |
| SCHEMBL2535613 | 0.78 | CNR1 (0.44) | CNR1MARS1SRD5A2 | |
| SCHEMBL1260378 | 0.75 | CNR1 (0.49) | CNR1MARS1SRD5A2 | |
| SCHEMBL2541063 | 0.71 | GABRA2 (0.44) | CNR1DPP4DPP8DPP9 | |
| SCHEMBL4513915 | 0.71 | CNR1 (0.44) | CNR1DPP4 | |
| SCHEMBL2535608 | 0.70 | CNR1 (0.62) | CNR1 | |
| SCHEMBL2539520 | 0.70 | CNR1 (0.45) | CNR1DPP4DPP8DPP9 | |
| SCHEMBL2570109 | 0.69 | ESR1 (0.51) | CNR1MARS1SRD5A2 | |
| SCHEMBL2906434 | 0.69 | HSD11B1 (0.47) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044072-B2 | Pyrrole derivatives, preparation thereof and therapeutic use thereof | SANOFI AVENTIS (FR) | 2011-10-25 | — | — | US | disclosed |