Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | MARS1 | P56192 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2539520 | 0.88 | CNR1 (0.45) | CNR1 | |
| SCHEMBL2535608 | 0.86 | CNR1 (0.62) | CNR1 | |
| SCHEMBL2535613 | 0.82 | CNR1 (0.44) | CNR1SRD5A2MARS1 | |
| SCHEMBL2541063 | 0.81 | GABRA2 (0.44) | CNR1 | |
| SCHEMBL2535616 | 0.79 | CNR1 (0.37) | CNR1SRD5A2MARS1 | |
| SCHEMBL1260378 | 0.78 | CNR1 (0.49) | CNR1SRD5A2MARS1 | |
| SCHEMBL2333021 | 0.78 | CNR1 (0.72) | CNR1 | |
| SCHEMBL2539560 | 0.77 | CNR1 (0.60) | CNR1 | |
| SCHEMBL2535011 | 0.77 | CNR1 (0.82) | CNR1 | |
| SCHEMBL23301686 | 0.75 | CCR2 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8044072-B2 | Pyrrole derivatives, preparation thereof and therapeutic use thereof | SANOFI AVENTIS (FR) | 2011-10-25 | — | — | US | disclosed |
| US-20090281116-A1 | PYRROLE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281116-A1 | PYRROLE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | PRMT9, PYCR1, EPOR | CNR1 177/4885SRD5A2 1557/4885MARS1 1784/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.