Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25357966 | 0.84 | ALDH1A1 (0.40) | CYP19A1ALDH1A1LMNAHTTBRD4 | |
| SCHEMBL16875669 | 0.80 | MDM2 (0.42) | CYP19A1ALDH1A1HTTKMT2AMAPT | |
| SCHEMBL31290998 | 0.76 | CRHBP (0.39) | CYP19A1ALDH1A1LMNAHTTBRD4 | |
| SCHEMBL31191034 | 0.76 | CRHBP (0.39) | CYP19A1ALDH1A1LMNAHTTBRD4 | |
| SCHEMBL25359757 | 0.75 | CYP19A1 (0.58) | CYP19A1BRD4KMT2AMAPTMEN1 | |
| SCHEMBL8511034 | 0.72 | MAPT (0.49) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| SCHEMBL18973787 | 0.72 | CYP19A1 (0.41) | CYP19A1ALDH1A1LMNABRD4KMT2A | |
| SCHEMBL30121849 | 0.70 | KDM4E (0.42) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| SCHEMBL29262050 | 0.70 | KDM4E (0.42) | ALDH1A1LMNAKMT2AMAPTMEN1 | |
| SCHEMBL15549951 | 0.68 | MAPT (0.41) | CYP19A1ALDH1A1LMNAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154896-A2 | TRKB LIGAND CONJUGATED COMPOUNDS AND USES THEREOF | ADARX PHARMACEUTICALS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |