Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PARL | Q9H300 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.46 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GPR183 | P32249 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25355903 | 0.93 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2LMNAPARLHTT | |
| SCHEMBL17394167 | 0.80 | PIP4K2A (0.47) | ALDH1A1LMNAHTTPIP4K2AGPR183 | |
| SCHEMBL25356264 | 0.80 | PKM (0.50) | PIP4K2AKMT2A | |
| SCHEMBL12169332 | 0.80 | PKM (0.57) | ALDH1A1SMN1; SMN2LMNAHTTKMT2A | |
| SCHEMBL16912993 | 0.80 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2LMNAPARLHTT | |
| SCHEMBL1519692 | 0.79 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2LMNAPARLHTT | |
| SCHEMBL4384605 | 0.79 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2LMNAPARLHTT | |
| SCHEMBL14132264 | 0.78 | POLB (0.62) | ALDH1A1SMN1; SMN2LMNAHSD11B1PIP4K2A | |
| SCHEMBL25354281 | 0.77 | PIP4K2A (0.53) | ALDH1A1SMN1; SMN2PIP4K2A | |
| SCHEMBL25332920 | 0.77 | SMN1; SMN2 (0.67) | ALDH1A1SMN1; SMN2LMNAPARLHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |