Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 4/20 | 0.44 |
| ▸ | F13A1 | P00488 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | TGM1 | P22735 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25356264 | 0.83 | PKM (0.50) | PIP4K2ANAMPTUSP2TSHRKDM4E | |
| SCHEMBL12169332 | 0.80 | PKM (0.57) | TSHRGAAALDH1A1SMN1; SMN2CYP2C19 | |
| SCHEMBL17394167 | 0.80 | PIP4K2A (0.47) | PIP4K2ANAMPTUSP2TSHRKDM4E | |
| SCHEMBL14132264 | 0.78 | POLB (0.62) | PIP4K2ATSHRGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL25359305 | 0.77 | ALDH1A1 (0.51) | PIP4K2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6945990 | 0.74 | USP2 (0.71) | USP2ALOX15MAPTGAAKDM4E | |
| SCHEMBL21514947 | 0.73 | POLB (0.50) | PIP4K2ANAMPTTSHRMAPTKDM4E | |
| SCHEMBL6951550 | 0.73 | GAA (0.69) | MAPTGAAALDH1A1SMN1; SMN2POLB | |
| SCHEMBL6944909 | 0.72 | ATM (0.63) | USP2TSHRALDH1A1SMN1; SMN2POLB | |
| SCHEMBL24058307 | 0.71 | POLB (0.61) | PIP4K2ANAMPTGAAPIK3C3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |