SCHEMBL25359665

SCHEMBL25359665

COC(=O)C(O)c1ccc(NC(=O)C(CCCCNC(c2ccccc2)(c2ccccc2)c2ccc(C)cc2)NC(=O)C(Cc2ccccc2)NC(=O)CCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])cc1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 15/20 0.38
▸ SSTR3 P32745 1/20 0.38
▸ CALCRL Q16602 1/20 0.36
▸ SIRT2 Q8IXJ6 1/20 0.34
▸ SIRT1 Q96EB6 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25359656 1.00 FOLH1 (0.38) FOLH1SSTR3CALCRLSIRT2SIRT1
SCHEMBL25362344 0.95 FOLH1 (0.38) FOLH1CALCRL
SCHEMBL25362331 0.95 FOLH1 (0.38) FOLH1CALCRL
SCHEMBL25362741 0.91 FOLH1 (0.38) FOLH1CALCRL
SCHEMBL25362754 0.91 FOLH1 (0.38) FOLH1CALCRL
SCHEMBL25361472 0.91 FOLH1 (0.38) FOLH1CALCRL
SCHEMBL25361811 0.91 FOLH1 (0.38) FOLH1CALCRL
SCHEMBL26024876 0.90 SSTR3 (0.42) FOLH1SSTR3CALCRL
SCHEMBL26015665 0.89 SSTR3 (0.41) FOLH1SSTR3CALCRL
SCHEMBL25358069 0.85 SIRT1 (0.35) FOLH1CALCRLSIRT2SIRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF ELUCIDA ONCOLOGY, INC. 2023-08-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230241243-A1 CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF NDC1, KIFC1, SDCBP FOLH1 433/4885SSTR3 3591/4885CALCRL 3746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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