Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 13/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013754 | 0.76 | KEAP1 (0.49) | MEN1KMT2AALDH1A1 | |
| SCHEMBL11333204 | 0.76 | PLCG1 (0.55) | MEN1KMT2A | |
| SCHEMBL696558 | 0.76 | MEN1 (0.49) | MEN1KMT2ASLC22A12HSD11B1ALDH1A1 | |
| SCHEMBL1148926 | 0.76 | MEN1 (0.49) | MEN1KMT2ASLC22A12HSD11B1ALDH1A1 | |
| SCHEMBL9040819 | 0.74 | CA1 (0.46) | MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL10292998 | 0.73 | KMT2A (0.53) | MEN1KMT2ASLC22A12HSD11B1ALDH1A1 | |
| SCHEMBL4565550 | 0.73 | MEN1 (0.46) | MEN1KMT2ASLC22A12HSD11B1ALDH1A1 | |
| SCHEMBL20714808 | 0.73 | KMT2A (0.46) | MEN1KMT2ASLC22A12HSD11B1ALDH1A1 | |
| SCHEMBL453331 | 0.72 | MMP1 (0.50) | KMT2AHSD11B1ALDH1A1CYP2C9 | |
| SCHEMBL28051 | 0.72 | PSIP1 (0.47) | MEN1KMT2AHSD11B1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023157030-A1 | PROCESS FOR THE PREPARATION OF 1-(4-(((6-AMINO-5-(4-PHENOXYPHENYL)PYRIMIDIN-4-YL) AMINO)METHYL)PIPERIDIN-1-YL)PROP-2-EN-1-ONE | MSN LABORATORIES PRIVATE LIMITED, R&D CENTER (IN) | 2023-08-24 | — | — | WO | disclosed |