Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.46 |
| ▸ | GRB2 | P62993 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25361270 | 1.00 | PTPN1 (0.46) | PTPN1GRB2SIRT1SIRT2MDM2 | |
| SCHEMBL30518584 | 0.92 | PTPN1 (0.45) | PTPN1GRB2SIRT1SIRT2MDM2 | |
| SCHEMBL31681574 | 0.88 | MDM2 (0.45) | SIRT1SIRT2MDM2SIRT5 | |
| SCHEMBL29649526 | 0.88 | MDM2 (0.45) | SIRT1SIRT2MDM2SIRT5 | |
| SCHEMBL25361716 | 0.88 | PTPN1 (0.43) | PTPN1GRB2SIRT1SIRT2 | |
| SCHEMBL25361722 | 0.88 | PTPN1 (0.43) | PTPN1GRB2SIRT1SIRT2 | |
| SCHEMBL29649620 | 0.84 | PTPN1 (0.42) | PTPN1GRB2SIRT1SIRT2MDM2 | |
| SCHEMBL29649613 | 0.84 | PTPN1 (0.42) | PTPN1GRB2SIRT1SIRT2MDM2 | |
| SCHEMBL22265232 | 0.83 | PTPN1 (0.44) | PTPN1GRB2MDM2SIRT5 | |
| SCHEMBL29649545 | 0.82 | MAPT (0.51) | PTPN1SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241243-A1 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | ELUCIDA ONCOLOGY, INC. | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230241243-A1 | CARRIER PARTICLE-DRUG CONJUGATES, SELF-IMMOLATIVE LINKERS, AND USES THEREOF | NDC1, KIFC1, SDCBP | PTPN1 754/4885GRB2 1083/4885SIRT1 2353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.