Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 3/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 5/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29649526 | 1.00 | MDM2 (0.45) | MDM2SIRT2SIRT1SIRT3TLR2 | |
| SCHEMBL30518584 | 0.95 | PTPN1 (0.45) | MDM2SIRT2SIRT1 | |
| SCHEMBL26066849 | 0.93 | MDM2 (0.47) | MDM2SIRT2SIRT1SIRT3TLR2 | |
| SCHEMBL30447741 | 0.93 | MDM2 (0.47) | MDM2SIRT2SIRT1SIRT3TLR2 | |
| SCHEMBL29649433 | 0.90 | MDM2 (0.44) | MDM2SIRT2SIRT1SIRT3TLR2 | |
| SCHEMBL25361944 | 0.89 | MDM2 (0.43) | MDM2SIRT2SIRT1SIRT3TLR2 | |
| SCHEMBL25361941 | 0.89 | MDM2 (0.43) | MDM2SIRT2SIRT1SIRT3TLR2 | |
| SCHEMBL29649545 | 0.89 | MAPT (0.51) | SIRT5 | |
| SCHEMBL29589438 | 0.88 | MDM2 (0.42) | MDM2SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL25361276 | 0.88 | PTPN1 (0.46) | MDM2SIRT2SIRT1SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250276074-A1 | BRM AND BRG1 TARGETING ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | PRELUDE THERAPEUTICS INCORPORATED | 2025-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250276074-A1 | BRM AND BRG1 TARGETING ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF | CRBN, RBX1, SMARCE1 | MDM2 86/4885SIRT2 3295/4885SIRT1 3063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.