Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25362258 | 1.00 | PKM (0.50) | PKMMEN1KMT2AKCNQ2MAPT | |
| SCHEMBL29001941 | 0.83 | ALDH1A1 (0.44) | KMT2ATSHRMME | |
| SCHEMBL8621288 | 0.83 | ALDH1A1 (0.44) | KMT2ATSHRMME | |
| SCHEMBL8621292 | 0.83 | ALDH1A1 (0.44) | KMT2ATSHRMME | |
| SCHEMBL27744044 | 0.78 | KMT2A (0.53) | MEN1KMT2AMAPTTSHRPOLB | |
| SCHEMBL30529599 | 0.78 | KMT2A (0.53) | MEN1KMT2AMAPTTSHRPOLB | |
| SCHEMBL13351329 | 0.77 | PKM (0.55) | PKMMEN1KMT2AKCNQ2MAPT | |
| SCHEMBL29001923 | 0.76 | RAB9A (0.46) | MEN1KMT2ATSHRNPSR1 | |
| SCHEMBL29001925 | 0.76 | RAB9A (0.46) | MEN1KMT2ATSHRNPSR1 | |
| SCHEMBL13318872 | 0.74 | PKM (0.60) | PKMMEN1KMT2AMMP8NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118742552-A | Five-membered and six-membered heterocyclic compounds and application thereof as protein kinase inhibitors | 上海轶诺药业有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-116655636-A | Five-membered and six-membered heterocyclic compounds and application thereof as protein kinase inhibitors | 上海轶诺药业有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2023155900-A1 | FIVE-MEMBERED AND SIX-MEMBERED HETEROCYCLIC COMPOUND, AND USE THEREOF AS PROTEIN KINASE INHIBITOR | 上海轶诺药业有限公司 | 2023-08-24 | — | — | WO | disclosed |