Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8621288 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HPGDKMT2ACYP2D6SRC | |
| SCHEMBL29001941 | 1.00 | ALDH1A1 (0.44) | ALDH1A1HPGDKMT2ACYP2D6SRC | |
| SCHEMBL25362258 | 0.83 | PKM (0.50) | KMT2AMMETSHR | |
| SCHEMBL25362256 | 0.83 | PKM (0.50) | KMT2AMMETSHR | |
| SCHEMBL28700643 | 0.83 | LMNA (0.45) | CYP2D6SRCLMNAMMEMAPK1 | |
| SCHEMBL14935643 | 0.83 | MME (0.47) | ALDH1A1HPGDKMT2ACYP2D6HPGDS | |
| SCHEMBL21274600 | 0.83 | MME (0.47) | ALDH1A1HPGDKMT2ACYP2D6HPGDS | |
| SCHEMBL27744044 | 0.82 | KMT2A (0.53) | ALDH1A1HPGDKMT2ALMNATSHR | |
| SCHEMBL30529599 | 0.82 | KMT2A (0.53) | ALDH1A1HPGDKMT2ALMNATSHR | |
| SCHEMBL8230711 | 0.81 | MME (0.41) | CYP2D6SRCLMNAMMEMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116655636-A | Five-membered and six-membered heterocyclic compounds and application thereof as protein kinase inhibitors | 上海轶诺药业有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-115916207-A | Five-membered and six-membered heterocyclic compounds and application thereof as protein receptor kinase inhibitors | 轶诺(浙江)药业有限公司 | 2023-04-04 | — | — | CN | disclosed |
| US-5767254-A | INCORPORATING IMINO-BOUND MOIETY | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 1998-06-16 | — | — | US | disclosed |
| US-5470949-A | Method for making amino acid glycosides and glycopeptides | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 1995-11-28 | — | — | US | disclosed |