Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30520111 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL25366229 | 0.85 | MAP4K4 (0.56) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL30519914 | 0.85 | MAP4K4 (0.56) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL29381457 | 0.79 | MAPT (0.50) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL24227568 | 0.79 | MAPT (0.50) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL25365981 | 0.78 | MAPT (0.46) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL30520022 | 0.78 | MAPT (0.46) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL25367687 | 0.77 | TGFBR1 (0.47) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL30520035 | 0.77 | TGFBR1 (0.47) | ALDH1A1MAPTLMNAMAPK1MEN1 | |
| SCHEMBL4110516 | 0.77 | ADORA2A (0.43) | ALDH1A1MAPTLMNAMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250243194-A1 | ANTAGONIST OF ADENOSINE RECEPTORS | JANSSEN PHARMACEUTICA NV (BE) | 2025-07-31 | — | — | US | disclosed |
| WO-2023144559-A1 | ANTAGONIST OF ADENOSINE RECEPTORS | AdoRx Therapeutics Limited (GB) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023144559-A1 | ANTAGONIST OF ADENOSINE RECEPTORS | AdoRx Therapeutics Limited (GB) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250243194-A1 | ANTAGONIST OF ADENOSINE RECEPTORS | ADORA2B, ADORA2A, ADORA1 | ALDH1A1 637/4885MAPT 4767/4885LMNA 2819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.