Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | BRS3 | P32247 | 9/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.34 |
| ▸ | USP9X | Q93008 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25368335 | 0.88 | TRPV4 (0.42) | TRPV4NAMPT | |
| Trifluoroacetic Acid SCHEMBL25373083 | 0.83 | TRPV4 (0.44) | TRPV4BRS3GAAKMT2ANR1I2 | |
| SCHEMBL27034279 | 0.83 | TRPV4 (0.44) | TRPV4BRS3NR1I2KDM4E | |
| SCHEMBL25371906 | 0.82 | TRPV4 (0.44) | TRPV4BRS3GAANR1I2KDM4E | |
| SCHEMBL30567044 | 0.82 | TRPV4 (0.44) | TRPV4BRS3GAANR1I2KDM4E | |
| SCHEMBL25369198 | 0.82 | TRPV4 (0.46) | TRPV4BRS3NR1I2KDM4E | |
| SCHEMBL25370429 | 0.82 | LMNA (0.33) | GAAUSP9XKDM4E | |
| SCHEMBL25371790 | 0.81 | TGM2 (0.39) | TRPV4NAMPT | |
| SCHEMBL25370521 | 0.81 | TGM2 (0.39) | TRPV4NAMPT | |
| SCHEMBL25369209 | 0.81 | TRPV4 (0.38) | TRPV4BRS3KMT2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164063-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-31 | — | — | WO | disclosed |