Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777177 | 0.77 | PIN1 (0.42) | SMN1; SMN2KMT2AMEN1PIN1L3MBTL1 | |
| SCHEMBL19975026 | 0.77 | PIN1 (0.42) | SMN1; SMN2KMT2AMEN1PIN1L3MBTL1 | |
| SCHEMBL19975259 | 0.75 | PIN1 (0.40) | SMN1; SMN2KMT2AMEN1PIN1L3MBTL1 | |
| SCHEMBL7412667 | 0.74 | ALDH1A1 (0.50) | SMN1; SMN2KMT2AMEN1GAAPIN1 | |
| SCHEMBL19975386 | 0.73 | POLB (0.43) | SMN1; SMN2KMT2AMEN1GAAPIN1 | |
| SCHEMBL18039394 | 0.73 | MEN1 (0.37) | SMN1; SMN2KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL27590398 | 0.70 | MMP8 (0.47) | SMN1; SMN2KMT2AMEN1GAAPIN1 | |
| SCHEMBL27483206 | 0.69 | HTT (0.43) | SMN1; SMN2KMT2AMEN1GAAPIN1 | |
| SCHEMBL5847971 | 0.69 | ALDH1A1 (0.45) | SMN1; SMN2KMT2AMEN1GAAL3MBTL1 | |
| SCHEMBL31016233 | 0.68 | KMT2A (0.50) | SMN1; SMN2KMT2AMEN1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146897-A1 | 2-SUBSTITUTED THIAZOLE HSD17B13 INHIBITORS AND USES THEREOF | INIPHARM, INC. (US) | 2023-08-03 | — | — | WO | disclosed |