Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 9/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 9/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.45 |
| ▸ | CDK4 | P11802 | 2/20 | 0.43 |
| ▸ | CCND1 | P24385 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.41 |
| ▸ | HTR3B | O95264 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12147196 | 0.83 | CHRNB2 (0.58) | CHRNB2CHRNA4AOC3ADRB1HTR3E | |
| SCHEMBL22876928 | 0.80 | CHRNB2 (0.57) | CHRNB2CHRNA4AOC3ADRB1HTR3E | |
| SCHEMBL4024508 | 0.80 | CHRNB2 (0.58) | CHRNB2CHRNA4AOC3ADRB1CDK4 | |
| SCHEMBL14341117 | 0.79 | CHRNB2 (0.54) | CHRNB2CHRNA4AOC3ADRB1CDK4 | |
| SCHEMBL20038429 | 0.76 | CHRNB2 (0.58) | CHRNB2CHRNA4ADRB1CDK4CCND1 | |
| SCHEMBL16838133 | 0.76 | NCF1 (0.59) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL24468574 | 0.75 | L3MBTL1 (0.53) | AOC3 | |
| SCHEMBL3917325 | 0.74 | CHRNB2 (0.64) | CHRNB2CHRNA4ADRB1HTR3EHTR3B | |
| SCHEMBL4323521 | 0.71 | AOC3 (0.54) | CHRNB2CHRNA4AOC3CDK4CCND1 | |
| SCHEMBL22912811 | 0.71 | HDAC2 (0.55) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260098024-A1 | PARP1 INHIBITORS AND USES THEREOF | XINTHERA INC (US) | 2026-04-09 | — | — | US | disclosed |
| EP-4469449-A1 | PARP1 INHIBITORS AND USES THEREOF | Xinthera, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| CN-118510767-A | PARP1 inhibitors and uses thereof | 新特拉有限公司 | 2024-08-16 | — | — | CN | disclosed |
| WO-2023146957-A1 | PARP1 INHIBITORS AND USES THEREOF | XINTHERA, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260098024-A1 | PARP1 INHIBITORS AND USES THEREOF | PARP1, PARP11, PARP16 | CHRNB2 2501/4885CHRNA4 1812/4885AOC3 2604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.