Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25377922 | 0.81 | PIM1 (0.32) | PIM1SRCGSK3ATGFBR1 | |
| SCHEMBL24286093 | 0.78 | PIM1 (0.37) | PIM1SRCGSK3AAPPTGFBR1 | |
| SCHEMBL24286094 | 0.68 | LRRK2 (0.44) | — | |
| SCHEMBL24286579 | 0.55 | ABL1 (0.47) | PIM1SRCGSK3ATGFBR1 | |
| SCHEMBL4468976 | 0.52 | GAA (0.36) | — | |
| SCHEMBL24875980 | 0.52 | PGR (0.46) | APP | |
| SCHEMBL16033289 | 0.51 | AHR (0.39) | APP | |
| SCHEMBL9235991 | 0.50 | HSD17B1 (0.40) | APP | |
| SCHEMBL21279637 | 0.50 | HSD17B1 (0.40) | APP | |
| SCHEMBL15856377 | 0.50 | METAP2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11744824-B2 | 2-amino-3-carbonyl imidazopyridine and pyrazolopyridine compounds | 1ST Biotherapeutics, Inc. (KR) | 2023-09-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11744824-B2 | 2-amino-3-carbonyl imidazopyridine and pyrazolopyridine compounds | NLRP3, NLRP1, KCNJ2 | PIM1 1243/4885SRC 2258/4885GSK3A 1778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.