SCHEMBL25377641

SCHEMBL25377641

CC(C)(O)C(C)(C)O.OB(O)Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
SLC6A2 P23975 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
CYP2C19 P33261 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
LMNA P02545 1/20 0.39
CYP2D6 P10635 1/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
TRPA1 O75762 1/20 0.38
ARG2 P78540 1/20 0.38
HIF1A Q16665 1/20 0.38
LIPE Q05469 1/20 0.37
FDPS P14324 1/20 0.36
NOS2 P35228 1/20 0.36
CALM1 P0DP23 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL219668 0.88 CA1 (0.56) CA1CA2TP53TSHRTRPA1
Ethylene Glycol SCHEMBL8392416 0.81 CA1 (0.50) CA1CA2LMNATP53TSHR
Phenethylboronic Acid SCHEMBL29219406 0.81 CA1 (0.76) CA1CA2ARG2TDP1
Benzyl Alcohol SCHEMBL29132362 0.80 TSHR (0.61) CA1CA2SLC6A2TAAR1CYP2C19
Benzyl Bromide SCHEMBL28160537 0.78 ALDH1A1 (0.58) CA1CA2SLC6A2TAAR1CYP2C19
Pyridine SCHEMBL1581039 0.77 CA1 (0.46) CA1CA2SLC6A2CYP2C19CYP1A2
SCHEMBL670441 0.77 LIPE (0.35) CA1CA2SLC6A2TAAR1CYP2C19
SCHEMBL28433271 0.76 CA1 (0.45) CA1CA2CYP2C19CYP1A2TSHR
SCHEMBL29253807 0.75 LIPE (0.44) CA1CA2SLC6A2TAAR1CYP2C19
Isobutylbenzene SCHEMBL29065698 0.75 TRPA1 (0.46) SLC6A2TAAR1CYP2C9LMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117945995-A Alkylated nitrogen-containing heterocyclic compound and preparation method and application thereof 中国科学院青海盐湖研究所 2024-04-30 CN disclosed
US-20230272002-A1 PHOTOREDOX PROTEIN MODIFICATION THE ROSALIND FRANKLIN INSTITUTE (GB) 2023-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230272002-A1 PHOTOREDOX PROTEIN MODIFICATION PPOX, CACYBP, BRI3BP CA1 1284/4885CA2 598/4885SLC6A2 4329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.