Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30482519 | 1.00 | LMNA (0.41) | LMNASMN1; SMN2ALDH1A1MDM2HTT | |
| SCHEMBL25380419 | 0.82 | LMNA (0.43) | LMNASMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL30519311 | 0.80 | SLC6A2 (0.36) | LMNASMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL25341461 | 0.80 | SLC6A2 (0.36) | LMNASMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL25377702 | 0.78 | RAB9A (0.42) | LMNASMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL25375690 | 0.78 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL30482509 | 0.78 | KMT2A (0.41) | LMNASMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL25379199 | 0.78 | KMT2A (0.41) | LMNASMN1; SMN2ALDH1A1HTTMAPT | |
| SCHEMBL25343113 | 0.77 | PTGS2 (0.35) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL30519319 | 0.77 | PTGS2 (0.35) | LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146512-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023146512-A1 | COMPOUNDS AND METHODS OF USE THEREOF | VIVACE THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |