Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.35 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | XPO1 | O14980 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25386554 | 1.00 | CTSL (0.40) | CTSLCNR2SLC6A9HSP90AA1HSP90AB1 | |
| SCHEMBL31486685 | 0.91 | CTSL (0.38) | CTSLCNR2HSP90AA1HSP90AB1XPO1 | |
| SCHEMBL25386927 | 0.81 | RORC (0.35) | CTSARORCCHRM3 | |
| SCHEMBL25386930 | 0.81 | RORC (0.35) | CTSARORCCHRM3 | |
| SCHEMBL25387205 | 0.80 | AKT1 (0.35) | CTSLCTSALMNA | |
| SCHEMBL25387208 | 0.80 | AKT1 (0.35) | CTSLCTSALMNA | |
| SCHEMBL25387434 | 0.80 | DRD2 (0.35) | CTSLCTSALMNA | |
| SCHEMBL25387437 | 0.80 | DRD2 (0.35) | CTSLCTSALMNA | |
| SCHEMBL25387520 | 0.79 | CTSA (0.35) | CTSA | |
| Hydrochloric Acid SCHEMBL25387304 | 0.76 | SLC9A1 (0.40) | CNR2SLC6A9HSP90AA1HSP90AB1CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023152042-A1 | ANTIMALARIAL HEXAHYDROPYRIMIDINE ANALOGUES | UCB Biopharma SRL (BE) | 2023-08-17 | — | — | WO | disclosed |