Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30668811 | 1.00 | PPARG (0.55) | PPARGL3MBTL1POLBATMADRA2C | |
| SCHEMBL18666146 | 0.89 | ADRA2C (0.54) | PPARGL3MBTL1POLBATMADRA2C | |
| SCHEMBL29660113 | 0.89 | ADRA2C (0.54) | PPARGL3MBTL1POLBATMADRA2C | |
| SCHEMBL18666199 | 0.81 | DEGS1 (0.49) | PPARGL3MBTL1POLBADRA2CGAA | |
| SCHEMBL18666149 | 0.81 | ALDH1A1 (0.55) | POLBMTNR1BTDP1KMT2ALMNA | |
| SCHEMBL18666157 | 0.81 | ALDH1A1 (0.48) | PPARGL3MBTL1POLBADRA2CGAA | |
| SCHEMBL18666150 | 0.80 | MTNR1B (0.47) | PPARGL3MBTL1ADRA2CGAAMTNR1B | |
| SCHEMBL18666151 | 0.79 | MTNR1B (0.63) | POLBMTNR1BTDP1KMT2ALMNA | |
| SCHEMBL21675770 | 0.79 | ALDH1A1 (0.45) | PPARGL3MBTL1POLBADRA2CGAA | |
| SCHEMBL30567101 | 0.79 | MTNR1B (0.63) | POLBMTNR1BTDP1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4490142-A2 | PCNA INHIBITORS AND USES THEREOF | City of Hope (US) | 2025-01-15 | — | — | EP | disclosed |
| WO-2023172880-A2 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2023-09-14 | — | — | WO | disclosed |
| WO-2023172880-A2 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2023-09-14 | — | — | WO | disclosed |