Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25387353 | 0.85 | L3MBTL1 (0.54) | L3MBTL1TDP1LMNAALDH1A1HPGD | |
| SCHEMBL25387355 | 0.85 | L3MBTL1 (0.54) | L3MBTL1TDP1LMNAALDH1A1HPGD | |
| SCHEMBL30567142 | 0.79 | L3MBTL1 (0.40) | L3MBTL1TDP1LMNAALDH1A1HPGD | |
| SCHEMBL30567132 | 0.77 | MDM2 (0.41) | — | |
| Toluene SCHEMBL28694057 | 0.72 | KIF11 (0.51) | — | |
| SCHEMBL30858815 | 0.70 | MEN1 (0.50) | L3MBTL1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL29221847 | 0.70 | MEN1 (0.50) | L3MBTL1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL28770107 | 0.70 | L3MBTL1 (0.60) | L3MBTL1TDP1LMNAALDH1A1HPGD | |
| SCHEMBL30567114 | 0.70 | MTNR1B (0.55) | L3MBTL1LMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL6290636 | 0.69 | S1PR1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4490142-A2 | PCNA INHIBITORS AND USES THEREOF | City of Hope (US) | 2025-01-15 | — | — | EP | disclosed |
| WO-2023172880-A2 | PCNA INHIBITORS AND USES THEREOF | CITY OF HOPE (US) | 2023-09-14 | — | — | WO | disclosed |