Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.49 |
| ▸ | ADK | P55263 | 8/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | MARK3 | P27448 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25388813 | 0.82 | LMNA (0.39) | YTHDC1ADKSRCLMNATP53 | |
| SCHEMBL29588944 | 0.79 | ADK (0.45) | YTHDC1ADKEGFRSRCPDE2A | |
| SCHEMBL17818402 | 0.79 | ADK (0.45) | YTHDC1ADKEGFRSRCPIK3CD | |
| SCHEMBL27890208 | 0.76 | ADK (0.55) | YTHDC1ADKEGFRSRCMAP4K4 | |
| SCHEMBL3605358 | 0.75 | ADK (0.49) | ADKSRCDYRK3ROCK2PRKD3 | |
| SCHEMBL18658456 | 0.75 | ADK (0.34) | ADKDYRK3ROCK2PRKD3MAP4K4 | |
| SCHEMBL1585102 | 0.75 | ADK (0.49) | ADKDYRK3ROCK2PRKD3MAP4K4 | |
| SCHEMBL23630525 | 0.74 | ADK (0.47) | YTHDC1ADKEGFRSRCPIK3CD | |
| SCHEMBL28057872 | 0.74 | EGFR (0.53) | YTHDC1ADKEGFRSRCPIK3CD | |
| SCHEMBL25141441 | 0.72 | ADK (0.43) | YTHDC1ADKEGFRSRCDYRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023169453-A1 | HETEROAROMATIC RING-CONTAINING ALKYNYL COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 中国科学院上海药物研究所 | 2023-09-14 | — | — | WO | disclosed |