SCHEMBL25389124

SCHEMBL25389124

CC(C)CNC(=O)C(C)(C)N1CCC(C#N)(c2cccc(F)c2F)CC1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ ADRA1D P25100 11/20 0.39
▸ ADRA1A P35348 11/20 0.39
▸ ADRA1B P35368 11/20 0.39
▸ BDKRB1 P46663 1/20 0.39
▸ PDE4A P27815 1/20 0.35
▸ PDE4B Q07343 1/20 0.35
▸ PDE4C Q08493 1/20 0.35
▸ PDE4D Q08499 1/20 0.35
▸ HDAC4 P56524 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ GPR119 Q8TDV5 1/20 0.34
▸ MC4R P32245 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26239136 0.84 LMNA (0.41) ADRA1DADRA1AADRA1BBDKRB1PDE4A
SCHEMBL26239138 0.84 BDKRB1 (0.40) ADRA1DADRA1AADRA1BBDKRB1PDE4A
SCHEMBL26239140 0.83 BDKRB1 (0.39) ADRA1DADRA1AADRA1BBDKRB1PDE4A
SCHEMBL26239143 0.82 BDKRB1 (0.42) ADRA1DADRA1AADRA1BBDKRB1PDE4A
SCHEMBL26239133 0.81 ADRA1D (0.49) ADRA1DADRA1AADRA1BPDE4APDE4B
SCHEMBL26239145 0.79 ADRA1D (0.39) ADRA1DADRA1AADRA1BBDKRB1PDE4A
SCHEMBL25388961 0.76 LMNA (0.40) ADRA1DADRA1AADRA1BLMNAGPR119
SCHEMBL26238713 0.74 LMNA (0.42) LMNAGPR119MC4R
SCHEMBL25388886 0.72 GPR119 (0.43) BDKRB1GPR119
SCHEMBL25388967 0.71 SMN1; SMN2 (0.47) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250280861-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2025-09-11 — — US disclosed
EP-4472947-A1 SWEETENER COMPOSITIONS Firmenich Incorporated (US) 2024-12-11 — — EP disclosed
WO-2023172415-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2023-09-14 — — WO disclosed
WO-2023172415-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2023-09-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250280861-A1 SWEETENER COMPOSITIONS GPR119, TAS2R50, TAS2R30 ADRA1D 4209/4885ADRA1A 4335/4885ADRA1B 4241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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