SCHEMBL25390175

SCHEMBL25390175

Cc1cccc(N2CCN(C(C)(C)C(=O)O)CC2)c1C

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.61
▸ LMNA P02545 6/20 0.57
▸ KMT2A Q03164 6/20 0.57
▸ MEN1 O00255 4/20 0.57
▸ MAPT P10636 6/20 0.56
▸ NPSR1 Q6W5P4 3/20 0.54
▸ TSHR P16473 4/20 0.53
▸ SMN1; SMN2 Q16637 2/20 0.53
▸ KDM4E B2RXH2 1/20 0.53
▸ ALOX15 P16050 1/20 0.53
▸ HSD17B10 Q99714 1/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.53
▸ MAPK1 P28482 2/20 0.52
▸ ADRB1 P08588 1/20 0.51
▸ GAA P10253 1/20 0.50
▸ HPGD P15428 1/20 0.50
▸ RAB9A P51151 2/20 0.49
▸ NPC1 O15118 1/20 0.49
▸ HTT P42858 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26238502 0.81 ALDH1A1 (0.55) ALDH1A1LMNAKMT2AMEN1MAPT
SCHEMBL26238518 0.80 ALDH1A1 (0.52) ALDH1A1LMNAKMT2AMEN1MAPT
SCHEMBL26238620 0.80 ALDH1A1 (0.52) ALDH1A1LMNAKMT2AMEN1MAPT
SCHEMBL25392645 0.80 RAB9A (0.60) ALDH1A1LMNAKMT2AMEN1MAPT
SCHEMBL11067105 0.80 ADRB1 (0.74) ALDH1A1LMNAKMT2AMEN1MAPT
SCHEMBL8759118 0.80 ALDH1A1 (0.77) ALDH1A1LMNAKMT2AMEN1MAPT
SCHEMBL26238618 0.79 ALDH1A1 (0.51) ALDH1A1LMNAKMT2AMEN1MAPT
SCHEMBL26238519 0.79 MAPT (0.53) ALDH1A1LMNAKMT2AMEN1MAPT
SCHEMBL26238503 0.79 ALDH1A1 (0.53) ALDH1A1LMNAKMT2AMEN1MAPT
SCHEMBL26238525 0.79 ALDH1A1 (0.48) ALDH1A1LMNAKMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250280861-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2025-09-11 — — US disclosed
EP-4472947-A1 SWEETENER COMPOSITIONS Firmenich Incorporated (US) 2024-12-11 — — EP disclosed
WO-2023172415-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2023-09-14 — — WO disclosed
WO-2023172415-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2023-09-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250280861-A1 SWEETENER COMPOSITIONS GPR119, TAS2R50, TAS2R30 ALDH1A1 1279/4885LMNA 4689/4885KMT2A 3161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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