SCHEMBL25390755

SCHEMBL25390755

COCc1cccc(C2CCN(C(COC)C(=O)NCC(C)C)CC2)c1F

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ASAH1 Q13510 1/20 0.38
▸ AOC3 Q16853 4/20 0.34
▸ P2RX3 P56373 1/20 0.33
▸ HCRTR2 O43614 2/20 0.33
▸ GPR119 Q8TDV5 1/20 0.33
▸ DRD2 P14416 2/20 0.33
▸ HTR2A P28223 2/20 0.33
▸ DRD3 P35462 2/20 0.33
▸ USP30 Q70CQ3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26239077 0.90 HCRTR2 (0.41) ASAH1HCRTR2GPR119
SCHEMBL26238972 0.80 ASAH1 (0.39) ASAH1AOC3P2RX3HCRTR2GPR119
SCHEMBL26239074 0.79 KCNH2 (0.44) —
SCHEMBL25388839 0.78 MEN1 (0.35) AOC3
SCHEMBL26238977 0.70 ASAH1 (0.41) ASAH1HCRTR2GPR119DRD2HTR2A
SCHEMBL26239145 0.70 ADRA1D (0.39) DRD2HTR2A
SCHEMBL26239068 0.69 P2RX3 (0.40) ASAH1P2RX3HCRTR2
SCHEMBL26238978 0.67 USP30 (0.43) ASAH1HCRTR2DRD2USP30
SCHEMBL25391308 0.66 PRCP (0.47) —
SCHEMBL26238976 0.65 ASAH1 (0.42) ASAH1HCRTR2GPR119DRD2HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250280861-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2025-09-11 — — US disclosed
EP-4472947-A1 SWEETENER COMPOSITIONS Firmenich Incorporated (US) 2024-12-11 — — EP disclosed
WO-2023172415-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2023-09-14 — — WO disclosed
WO-2023172415-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2023-09-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250280861-A1 SWEETENER COMPOSITIONS GPR119, TAS2R50, TAS2R30 ASAH1 239/4885AOC3 2739/4885P2RX3 2797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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