SCHEMBL25391308

SCHEMBL25391308

CC(C)CNC(=O)C(CCO)N1CCC(c2ccccc2)CC1

nearest known ligand 0.55

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ PRCP P42785 4/20 0.47
▸ KCNH2 Q12809 1/20 0.45
▸ HRH3 Q9Y5N1 1/20 0.45
▸ OPRM1 P35372 2/20 0.44
▸ SLC18A3 Q16572 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26239074 0.85 KCNH2 (0.44) PRCPKCNH2HRH3OPRM1SLC18A3
SCHEMBL26238906 0.84 KCNH2 (0.50) PRCPKCNH2HRH3OPRM1SLC18A3
SCHEMBL4029855 0.76 PRMT5 (0.58) PRCPKCNH2HRH3
SCHEMBL26238905 0.74 PRCP (0.58) PRCPSLC18A3
SCHEMBL25389373 0.73 PRCP (0.48) PRCPKCNH2HRH3OPRM1SLC18A3
SCHEMBL19370816 0.73 KCNH2 (0.43) PRCPKCNH2HRH3OPRM1SLC18A3
SCHEMBL27498941 0.72 KCNH2 (0.60) PRCPKCNH2HRH3OPRM1SLC18A3
SCHEMBL24029313 0.71 OPRM1 (0.47) PRCPKCNH2HRH3OPRM1SLC18A3
SCHEMBL26239083 0.70 PRCP (0.45) PRCPKCNH2HRH3OPRM1SLC18A3
SCHEMBL15840473 0.70 ADAMTS5 (0.58) PRCPKCNH2HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250280861-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2025-09-11 — — US disclosed
EP-4472947-A1 SWEETENER COMPOSITIONS Firmenich Incorporated (US) 2024-12-11 — — EP disclosed
WO-2023172415-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2023-09-14 — — WO disclosed
WO-2023172415-A1 SWEETENER COMPOSITIONS FIRMENICH INCORPORATED (US) 2023-09-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250280861-A1 SWEETENER COMPOSITIONS GPR119, TAS2R50, TAS2R30 PRCP 1490/4885KCNH2 3794/4885HRH3 2679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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