SCHEMBL25396506

SCHEMBL25396506

Cc1nn(C)cc1C(=O)NCC1=NOC(Cc2ccccc2)(C(=O)N[C@@H](CC(C)C)B(O)O)C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PSMB5 P28074 18/20 0.39
▸ PSMB8 P28062 2/20 0.38
▸ PSMB1 P20618 7/20 0.36
▸ PSMB2 P49721 7/20 0.36
▸ PSMB11 A5LHX3 1/20 0.35
▸ PSMA7 O14818 1/20 0.35
▸ PSMA1 P25786 1/20 0.35
▸ PSMA2 P25787 1/20 0.35
▸ PSMA3 P25788 1/20 0.35
▸ PSMA4 P25789 1/20 0.35
▸ PSMB9 P28065 1/20 0.35
▸ PSMA5 P28066 1/20 0.35
▸ PSMB4 P28070 1/20 0.35
▸ PSMB6 P28072 1/20 0.35
▸ PSMB10 P40306 1/20 0.35
▸ PSMB3 P49720 1/20 0.35
▸ PSMA6 P60900 1/20 0.35
▸ PSMA8 Q8TAA3 1/20 0.35
▸ PSMB7 Q99436 1/20 0.35
▸ USP2 O75604 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25396509 1.00 PSMB5 (0.39) PSMB5PSMB8PSMB1PSMB2PSMB11
SCHEMBL25438517 0.92 PSMB5 (0.38) PSMB5PSMB8PSMB1PSMB2PSMB9
SCHEMBL25438514 0.92 PSMB5 (0.38) PSMB5PSMB8PSMB1PSMB2PSMB9
SCHEMBL25400042 0.88 PSMB8 (0.45) PSMB5PSMB8PSMB1PSMB2PSMB11
SCHEMBL25400044 0.88 PSMB8 (0.45) PSMB5PSMB8PSMB1PSMB2PSMB11
SCHEMBL25399263 0.87 PSMB5 (0.48) PSMB5PSMB8PSMB1PSMB2
SCHEMBL25399267 0.87 PSMB5 (0.48) PSMB5PSMB8PSMB1PSMB2
SCHEMBL25400991 0.87 PSMB5 (0.39) PSMB5PSMB8PSMB1PSMB2
SCHEMBL25400987 0.87 PSMB5 (0.39) PSMB5PSMB8PSMB1PSMB2
SCHEMBL25402569 0.86 PSMB5 (0.39) PSMB5PSMB8PSMB1PSMB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570675-B2 Boronic acid compounds LG CHEM, LTD. (KR) 2026-03-10 — — US disclosed
US-20240101579-A1 BORONIC ACID COMPOUNDS LG CHEM, LTD. (KR) 2024-03-28 — — US disclosed
EP-4242213-A1 BORONIC ACID COMPOUND Lg Chem, Ltd. (KR) 2023-09-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570675-B2 Boronic acid compounds PSMB6, PSMB3, PSMB2 PSMB5 10/4885PSMB8 5/4885PSMB1 4/4885
US-20240101579-A1 BORONIC ACID COMPOUNDS PSMB11, PSMB1, BACH1 PSMB5 7/4885PSMB8 28/4885PSMB1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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