SCHEMBL25397252

SCHEMBL25397252

CCOC([SiH3])(CCCC#N)OCC

nearest known ligand 0.41

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25398609 0.94 TSHR (0.39) TSHRMEN1KMT2A
SCHEMBL25395739 0.87 MEN1 (0.42) TSHRMEN1KMT2A
SCHEMBL2501154 0.78 TSHR (0.39) TSHRMEN1KMT2A
SCHEMBL21332490 0.75 LMNA (0.30) TSHR
SCHEMBL25399987 0.72 TSHR (0.37) TSHR
SCHEMBL21723155 0.71 TSHR (0.38) TSHRMEN1KMT2A
SCHEMBL29124493 0.71 TSHR (0.38) TSHRMEN1KMT2A
SCHEMBL3924179 0.71
SCHEMBL302858 0.71 CYP1A2 (0.31) TSHRMEN1KMT2A
SCHEMBL6889414 0.71 TSHR (0.38) TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313681-A1 SUBSTRATES WITH RESIN COMPOSITION ADHERED THERETO AND METHODS FOR IMPROVING ADHESION TO A SUBSTRATE MOMENTIVE PERFORMANCE MAT INC (US) 2025-10-09 US disclosed
US-20250179221-A1 HIGHLY FUNCTIONALIZED STABLE HYDROCARBYLOXYSILYL POLYDIENES AND POLYDIENE COPOLYMERS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC 2025-06-05 US disclosed
CN-118900883-A Highly functionalized stable hydrocarbyloxysilyl polydienes and polydiene copolymers 普利司通美国轮胎运营有限责任公司 2024-11-05 CN disclosed
CN-118382664-A Condensation curable composition 迈图高新材料公司 2024-07-23 CN disclosed
US-11760900-B2 Condensation curable composition MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2023-09-19 US disclosed
WO-2023158819-A1 HIGHLY FUNCTIONALIZED STABLE HYDROCARBYLOXYSILYL POLYDIENES AND POLYDIENE COPOLYMERS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2023-08-24 WO disclosed
WO-2023076316-A1 CONDENSATION CURABLE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2023-05-04 WO disclosed
US-20230127458-A1 CONDENSATION CURABLE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2023-04-27 US disclosed