SCHEMBL2539751

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2538719	0.82	F10 (0.39)	F10ALDH1A1MEN1MAPTKMT2A
	SCHEMBL143175	0.81	ALDH1A1 (0.54)	F10ALDH1A1SMN1; SMN2KDM4ECYP1A2
	SCHEMBL2645575	0.80	DDB1 (0.41)	F10ALDH1A1SMN1; SMN2KDM4ECYP1A2
	SCHEMBL142777	0.78	F10 (0.44)	F10ALDH1A1KDM4E
	SCHEMBL92819	0.78	KDM4E (0.57)	F10ALDH1A1SMN1; SMN2KDM4ECYP1A2
	SCHEMBL4212713	0.78	F10 (0.56)	F10ALDH1A1MEN1KMT2AATM
	SCHEMBL29348735	0.78	F10 (0.52)	F10ALDH1A1SMN1; SMN2KDM4ECYP1A2
	SCHEMBL1277801	0.78	FAAH (0.43)	F10ALDH1A1SMN1; SMN2KDM4ECYP1A2
	SCHEMBL142916	0.78	MEN1 (0.54)	F10ALDH1A1MEN1MAPTKMT2A
	SCHEMBL76912	0.78	SMN1; SMN2 (0.52)	F10ALDH1A1SMN1; SMN2KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.