Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 8/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143175 | 0.81 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1ATMF10GAA | |
| SCHEMBL2645575 | 0.80 | DDB1 (0.41) | SMN1; SMN2ALDH1A1ATMF10CA12 | |
| SCHEMBL14320317 | 0.79 | MAOA (0.53) | SMN1; SMN2ALDH1A1ALOX15HTTATM | |
| SCHEMBL142916 | 0.78 | MEN1 (0.54) | ALDH1A1HTTF10GAA | |
| SCHEMBL92819 | 0.78 | KDM4E (0.57) | SMN1; SMN2ALDH1A1HTTF10CA1 | |
| SCHEMBL2539751 | 0.78 | F10 (0.39) | SMN1; SMN2ALDH1A1ATMF10CA12 | |
| SCHEMBL29348735 | 0.78 | F10 (0.52) | SMN1; SMN2ALDH1A1HTTF10GAA | |
| SCHEMBL142777 | 0.78 | F10 (0.44) | ALDH1A1F10KDM4E | |
| SCHEMBL1277801 | 0.78 | FAAH (0.43) | SMN1; SMN2ALDH1A1F10KDM4ECYP1A2 | |
| SCHEMBL4212713 | 0.78 | F10 (0.56) | ALDH1A1ALOX15HTTATMF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382836-A | A kind of preparation method of the ketone of 1 (4 aminophenyl) 1H pyridines 2 | 吴赣药业（苏州）有限公司 | 2017-11-24 | — | — | CN | claimed |
| CN-102464658-A | Oxazolidinone derivative and preparation method and application thereof | TIANJIN INST PHARM RESEARCH | 2012-05-23 | — | — | CN | claimed |
| US-7601752-B2 | Pyrrolidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-10-13 | — | — | US | claimed |
| US-7205318-B2 | Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-04-17 | — | — | US | claimed |
| CN-115073470-B | Pyrrolopyrimidinone derivative, and preparation method and application thereof | 南京中瑞药业有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-115073470-A | Pyrrolopyrimidinone derivative and preparation method and application thereof | 南京中瑞药业有限公司 | 2022-09-20 | — | — | CN | disclosed |
| EP-3313837-B1 | CARBOLINE ANTIPARASITICS | ZOETIS SERVICES LLC (US) | 2020-09-09 | — | — | EP | disclosed |
| US-10752624-B2 | Kinase inhibitors | ORIGENIS GMBH (DE) | 2020-08-25 | — | — | US | disclosed |
| US-20200140436-A1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2020-05-07 | — | — | US | disclosed |
| US-20200079754-A1 | INHIBITORS OF BRUTONS TYROSINE KINASE | PHARMACYCLICS LLC (US) | 2020-03-12 | — | — | US | disclosed |
| US-10570129-B2 | Carboline antiparasitics | ZOETIS SERVICES LLC (US) | 2020-02-25 | — | — | US | disclosed |
| US-20200031822-A1 | CARBOLINE ANTIPARASITICS | ZOETIS SERVICES LLC (US) | 2020-01-30 | — | — | US | disclosed |
| US-20040077635-A1 | Lactam-containing diaminoalkyl, beta-aminoacids, alpha-aminoacids and derivatives thereof as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2004-04-22 | — | — | US | disclosed |
| WO-2004031145-A2 | LACTAM-CONTAINING DIAMINOALKYL, BETA-AMINOACIDS, ALPHA-AMINOACIDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-04-15 | — | — | WO | disclosed |
| WO-2004017963-A1 | BENZIMIDAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2004-03-04 | — | — | WO | disclosed |
| EP-1368341-A1 | PHENYL DERIVATIVES 3 | MERCK PATENT GmbH (DE) | 2003-12-10 | — | — | EP | disclosed |
| EP-1351938-A1 | PHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-10-15 | — | — | EP | disclosed |
| WO-2003013531-A1 | PHENYL DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-02-20 | — | — | WO | disclosed |
| WO-2002074765-A1 | PHENYL DERIVATIVES 3 | MERCK PATENT GMBH (DE) | 2002-09-26 | — | — | WO | disclosed |
| WO-2002057236-A1 | PHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200079754-A1 | INHIBITORS OF BRUTONS TYROSINE KINASE | BTK, LYN, LCK | SMN1; SMN2 4365/4885ALDH1A1 4726/4885ALOX15 2798/4885 |
| US-10570129-B2 | Carboline antiparasitics | ADRA1D, DRD1, CHRM1 | SMN1; SMN2 1794/4885ALDH1A1 381/4885ALOX15 3840/4885 |
| US-20040077635-A1 | Lactam-containing diaminoalkyl, beta-aminoacids, alpha-aminoacids and derivatives thereof as factor Xa inhibitors | PEPD, METAP1, XPNPEP1 | SMN1; SMN2 2587/4885ALDH1A1 1770/4885ALOX15 2989/4885 |
| US-20200140436-A1 | LACTAM-CONTAINING COMPOUNDS AND DERIVATIVES THEREOF AS FACTOR XA INHIBITORS | F12, F2, CPB1 | SMN1; SMN2 3212/4885ALDH1A1 3406/4885ALOX15 3063/4885 |
| US-10752624-B2 | Kinase inhibitors | LRRK2, MYLK2, MYLK | SMN1; SMN2 986/4885ALDH1A1 4184/4885ALOX15 2780/4885 |
| US-20200031822-A1 | CARBOLINE ANTIPARASITICS | DRD1, ADRA1D, DRD2 | SMN1; SMN2 1951/4885ALDH1A1 334/4885ALOX15 3584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.