SCHEMBL25399672

SCHEMBL25399672

CC(C)C[C@H](NC(=O)C1CC(CNC(=O)C2CCCc3ccccc32)=NO1)B(O)O

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PSMB5 P28074 16/20 0.56
▸ PRMT5 O14744 1/20 0.42
▸ WDR77 Q9BQA1 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.39
▸ USP2 O75604 1/20 0.38
▸ PSMB8 P28062 1/20 0.37
▸ TAOK1 Q7L7X3 1/20 0.36
▸ TAOK3 Q9H2K8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25399678 1.00 PSMB5 (0.56) PSMB5PRMT5WDR77ALDH1A1USP2
SCHEMBL27181382 0.84 PSMB5 (0.42) PSMB5PSMB8
SCHEMBL27181385 0.84 PSMB5 (0.42) PSMB5PSMB8
SCHEMBL29846776 0.81 PRMT5 (0.44) PSMB5PRMT5WDR77ALDH1A1
SCHEMBL25397879 0.80 PSMB5 (0.62) PSMB5PSMB8
SCHEMBL25397885 0.80 PSMB5 (0.62) PSMB5PSMB8
SCHEMBL25400915 0.80 PSMB5 (0.46) PSMB5PSMB8
SCHEMBL25400906 0.80 PSMB5 (0.46) PSMB5PSMB8
SCHEMBL25400733 0.79 PSMB5 (0.57) PSMB5PSMB8
SCHEMBL25400738 0.79 PSMB5 (0.57) PSMB5PSMB8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570675-B2 Boronic acid compounds LG CHEM, LTD. (KR) 2026-03-10 — — US disclosed
US-20240101579-A1 BORONIC ACID COMPOUNDS LG CHEM, LTD. (KR) 2024-03-28 — — US disclosed
EP-4242213-A1 BORONIC ACID COMPOUND Lg Chem, Ltd. (KR) 2023-09-13 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570675-B2 Boronic acid compounds PSMB6, PSMB3, PSMB2 PSMB5 10/4885PRMT5 4297/4885WDR77 2592/4885
US-20240101579-A1 BORONIC ACID COMPOUNDS PSMB11, PSMB1, BACH1 PSMB5 7/4885PRMT5 4016/4885WDR77 576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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