Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSB | P07858 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 6/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25224247 | 0.80 | CACNA1G (0.46) | ALDH1A1EPHX1DPP7 | |
| SCHEMBL30203991 | 0.79 | KMT2A (0.58) | CTSKKDM1AMAOB | |
| SCHEMBL5692127 | 0.78 | CTSL (0.67) | CTSLCTSBCTSKALDH1A1GAA | |
| SCHEMBL562870 | 0.77 | ALDH1A1 (0.68) | CTSLCTSBCTSKALDH1A1GAA | |
| SCHEMBL3198466 | 0.77 | ALDH1A1 (0.64) | CTSLCTSBCTSKALDH1A1GAA | |
| SCHEMBL3948461 | 0.77 | ALDH1A1 (0.85) | CTSLCTSBCTSKALDH1A1GAA | |
| SCHEMBL3948456 | 0.77 | ALDH1A1 (0.85) | CTSLCTSBCTSKALDH1A1GAA | |
| SCHEMBL381922 | 0.77 | ALDH1A1 (0.85) | CTSLCTSBCTSKALDH1A1GAA | |
| SCHEMBL25568205 | 0.76 | ALDH1A1 (0.67) | CTSLCTSBCTSKALDH1A1GAA | |
| SCHEMBL28001597 | 0.76 | ALDH1A1 (0.67) | CTSLCTSBCTSKALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023177233-A1 | NOVEL COMPOUND AND USE THEREOF FOR INHIBITING CHECKPOINT KINASE 2 | (주)아름테라퓨틱스 | 2023-09-21 | — | — | WO | disclosed |