SCHEMBL25401698

SCHEMBL25401698

Cc1nc2c(C(=O)O)cccn2c1Cl

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.51
CASP1 P29466 1/20 0.51
CASP7 P55210 1/20 0.51
HSD17B10 Q99714 1/20 0.51
ALDH1A1 P00352 6/20 0.43
DHODH Q02127 2/20 0.41
HPGD P15428 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CA12 O43570 2/20 0.38
CA2 P00918 2/20 0.38
CA9 Q16790 2/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.37
MAPT P10636 1/20 0.37
CYP1A2 P05177 1/20 0.37
GLA P06280 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9087301 0.84 SMN1; SMN2 (0.44) KDM4EHSD17B10ALDH1A1SMN1; SMN2LMNA
SCHEMBL9081526 0.81 KDM4E (0.51) KDM4ECASP1CASP7HSD17B10ALDH1A1
SCHEMBL2315704 0.79 KDM4E (0.49) KDM4ECASP1CASP7HSD17B10ALDH1A1
SCHEMBL24517983 0.76 KDM4E (0.50) KDM4EHSD17B10ALDH1A1HPGDSMN1; SMN2
SCHEMBL9090196 0.76 KDM4E (0.52) KDM4ECASP1CASP7HSD17B10ALDH1A1
SCHEMBL9086378 0.76 KDM4E (0.46) KDM4ECASP1CASP7HSD17B10ALDH1A1
SCHEMBL9090341 0.75 HSD17B10 (0.45) KDM4ECASP1CASP7HSD17B10ALDH1A1
SCHEMBL31257935 0.74 KDM4E (0.64) KDM4ECASP1CASP7HSD17B10ALDH1A1
SCHEMBL3603947 0.74 SMN1; SMN2 (0.51) KDM4ECASP1CASP7HSD17B10ALDH1A1
SCHEMBL9090346 0.74 ATP4A (0.47) KDM4ECASP1CASP7HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570675-B2 Boronic acid compounds LG CHEM, LTD. (KR) 2026-03-10 US disclosed
US-20240101579-A1 BORONIC ACID COMPOUNDS LG CHEM, LTD. (KR) 2024-03-28 US disclosed
EP-4242213-A1 BORONIC ACID COMPOUND Lg Chem, Ltd. (KR) 2023-09-13 EP disclosed
CN-116568310-A Boric acid compounds 株式会社LG化学 2023-08-08 CN disclosed
WO-2022123530-A1 BORONIC ACID COMPOUND 주식회사 엘지화학 2022-06-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570675-B2 Boronic acid compounds PSMB6, PSMB3, PSMB2 KDM4E 3458/4885CASP1 1367/4885CASP7 1831/4885
US-20240101579-A1 BORONIC ACID COMPOUNDS PSMB11, PSMB1, BACH1 KDM4E 2004/4885CASP1 349/4885CASP7 1033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.