SCHEMBL2540263

SCHEMBL2540263

Cc1cc(OC(=O)OC(C)(C)C)ccc1OC(=O)OC(C)(C)C

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.56
CA2 P00918 1/20 0.44
KDM1A O60341 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.38
VDR P11473 1/20 0.37
KMT2A Q03164 3/20 0.37
BRD4 O60885 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPC1 O15118 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ACHE P22303 1/20 0.35
AR P10275 1/20 0.35
AAK1 Q2M2I8 1/20 0.34
MAPKAPK2 P49137 1/20 0.34
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27686098 0.86 ELANE (0.59) ELANECA2KDM1AL3MBTL1KMT2A
SCHEMBL4622585 0.83 ELANE (0.56) ELANECA2KDM1AL3MBTL1ALDH1A1
SCHEMBL17355754 0.82 ELANE (0.54) ELANECA2KDM1AL3MBTL1NPC1
SCHEMBL5907902 0.81 ELANE (0.53) ELANECA2KDM1AL3MBTL1KMT2A
SCHEMBL16785668 0.81 ELANE (0.53) ELANECA2KDM1AKMT2AKDM4E
SCHEMBL4061539 0.80 ELANE (0.65) ELANECA2KDM1AL3MBTL1KMT2A
SCHEMBL4061370 0.80 ELANE (0.81) ELANECA2KDM1AL3MBTL1KMT2A
SCHEMBL15074321 0.80 ALDH1A1 (0.41) ELANEBRD4KDM4EALDH1A1SMN1; SMN2
SCHEMBL18047570 0.79 ELANE (0.62) ELANECA2KDM1AKMT2AKDM4E
SCHEMBL10356768 0.78 ELANE (0.50) ELANECA2KDM1AL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140342291-A1 Novel Dual-Tone Resist Formulations And Methods BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-11-20 US disclosed
WO-2011133680-A2 NOVEL DUAL-TONE RESIST FORMULATIONS AND METHODS BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM (US) 2011-10-27 WO disclosed
US-20110262860-A1 NOVEL DUAL-TONE RESIST FORMULATIONS AND METHODS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS 2011-10-27 US disclosed