SCHEMBL17355754

SCHEMBL17355754

Cc1cc(OC(=O)OC(C)(C)C)ccc1F

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.54
CA2 P00918 1/20 0.43
KDM1A O60341 1/20 0.41
POLB P06746 1/20 0.39
MAPT P10636 1/20 0.39
CHEK2 O96017 2/20 0.36
NPC1 O15118 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ACHE P22303 1/20 0.34
RAB9A P51151 1/20 0.34
MTNR1A P48039 1/20 0.34
MTNR1B P49286 1/20 0.34
APP P05067 1/20 0.34
HDAC3 O15379 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17286544 0.87 ELANE (0.57) ELANECA2KDM1APOLBMAPT
SCHEMBL27686098 0.85 ELANE (0.59) ELANECA2KDM1AMAPTNPC1
SCHEMBL2540263 0.82 ELANE (0.56) ELANECA2KDM1ANPC1TDP1
SCHEMBL4622585 0.82 ELANE (0.56) ELANECA2KDM1APOLBMAPT
SCHEMBL17355743 0.81 RAB9A (0.42) MAPTNPC1TDP1RAB9A
SCHEMBL18089748 0.81 ELANE (0.51) ELANECA2KDM1AMAPTMTNR1A
SCHEMBL17356459 0.81 ELANE (0.51) ELANECA2KDM1APOLBMAPT
SCHEMBL17355717 0.80 ELANE (0.55) ELANECA2POLBMAPT
SCHEMBL5907902 0.79 ELANE (0.53) ELANECA2KDM1AMAPTNPC1
SCHEMBL4061539 0.79 ELANE (0.65) ELANECA2KDM1APOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE UBE INDUSTRIES, LTD. (JP) 2015-12-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150372349-A1 NON-AQUEOUS ELECTROLYTE AND ELECTRICITY STORAGE DEVICE HCN2, SCO2, HCN1 ELANE 570/4885CA2 286/4885KDM1A 1481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.