Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.41 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10915289 | 0.82 | ATAD2 (0.38) | POLBNPSR1NQO1ATAD2KDM4E | |
| Hydrochloric Acid SCHEMBL10915873 | 0.80 | ATAD2 (0.36) | POLBNPSR1NQO1ATAD2MAPT | |
| SCHEMBL25164695 | 0.77 | POLB (0.33) | POLBNPSR1NQO1SMN1; SMN2GAA | |
| SCHEMBL27916882 | 0.73 | POLB (0.46) | POLBNPSR1NQO1ALOX15HSD17B10 | |
| SCHEMBL8894016 | 0.71 | POLB (0.55) | POLBNPSR1KDM4EMAPTALDH1A1 | |
| SCHEMBL28167081 | 0.71 | ESR1 (0.42) | ALDH1A1 | |
| SCHEMBL8521071 | 0.69 | CYP1A2 (0.44) | KDM4EMAPTALDH1A1NFKB1CASP3 | |
| SCHEMBL91340 | 0.69 | ALDH1A1 (0.45) | POLBNPSR1ATAD2KDM4EMAPT | |
| SCHEMBL22991968 | 0.69 | SMN1; SMN2 (0.39) | POLBNPSR1NQO1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6027678 | 0.67 | TYMP (0.46) | KDM4EALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007492-A1 | USE OF 4-HYDRAZONO-1,4-DIHYDRO-PYRIDINE AND/OR 4-HYDRAZINO-PYRIDINE DERIVATIVES FOR TREATMENT OF HYPERTENSION AND CONGESTIVE HEART FAILURE | THE UPJOHN COMPANY (US) | 1994-04-14 | — | — | WO | claimed |
| US-8043385-B2 | Composition oxidation colouring of keratinic fibres, containing a cationic cellulose ether, a metasilicate and oxidation dyes, method for oxidation colouring and uses thereof | L'OREAL S.A. (FR) | 2011-10-25 | — | — | US | disclosed |
| US-20100263138-A1 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | L'OREAL S.A. (FR) | 2010-10-21 | — | — | US | disclosed |
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |
| WO-1994007492-A1 | USE OF 4-HYDRAZONO-1,4-DIHYDRO-PYRIDINE AND/OR 4-HYDRAZINO-PYRIDINE DERIVATIVES FOR TREATMENT OF HYPERTENSION AND CONGESTIVE HEART FAILURE | THE UPJOHN COMPANY (US) | 1994-04-14 | — | — | WO | disclosed |
| US-4297301-A | A 4H-PYRAN-4-ONE OR N-ALKYL-4-PYRIDONE CATALYST FOR THE PHOSGENATION OF AN ACID OR ANHYDRIDE | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1981-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100263138-A1 | COMPOSITION OXIDATION COLOURING OF KERATINIC FIBRES, CONTAINING A CATIONIC CELLULOSE ETHER, A METASILICATE AND OXIDATION DYES, METHOD FOR OXIDATION COLOURING AND USES THEREOF | KRT18, TUBB3, VIM | POLB 1108/4885NPSR1 3861/4885NQO1 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.