Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2540575 | 0.69 | POLB (0.43) | SMN1; SMN2POLBNPSR1NQO1ALDH1A1 | |
| SCHEMBL27916882 | 0.67 | POLB (0.46) | POLBNPSR1NQO1PDE4BALOX15 | |
| SCHEMBL12541553 | 0.65 | ALDH1A1 (0.46) | SMN1; SMN2POLBNPSR1ALDH1A1CA9 | |
| SCHEMBL11597619 | 0.64 | SMN1; SMN2 (0.35) | SMN1; SMN2 | |
| SCHEMBL10915289 | 0.60 | ATAD2 (0.38) | SMN1; SMN2POLBNPSR1NQO1ALDH1A1 | |
| SCHEMBL9370346 | 0.59 | POLB (0.64) | SMN1; SMN2POLBNPSR1ALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL10915873 | 0.59 | ATAD2 (0.36) | SMN1; SMN2POLBNPSR1NQO1ALDH1A1 | |
| SCHEMBL22746567 | 0.57 | KDM4E (0.43) | POLBNPSR1PDE4BALDH1A1HSD17B10 | |
| SCHEMBL28943176 | 0.57 | — | — | |
| SCHEMBL791652 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3777979-A1 | ANTI-INFLAMMATORY COMPOUND AND PREPARATION AND USE THEREOF | Vivavision Biotech, Inc. (CN) | 2021-02-17 | — | — | EP | disclosed |