Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.41 |
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | ALB | P02768 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.33 |
| ▸ | EEF2K | O00418 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30418928 | 0.88 | EGLN2 (0.38) | EGLN2KHKTRPV4TTRALB | |
| SCHEMBL2437496 | 0.88 | EGLN2 (0.38) | EGLN2KHKTRPV4TTRALB | |
| SCHEMBL15321404 | 0.84 | EGLN2 (0.38) | EGLN2KHKTTRALBHTT | |
| SCHEMBL10120595 | 0.84 | CA1 (0.44) | EGLN2KHKVCAM1 | |
| SCHEMBL14247428 | 0.84 | MEN1 (0.48) | EGLN2KHKTTRALBMEN1 | |
| SCHEMBL1997670 | 0.84 | TTR (0.48) | EGLN2KHKTRPV4TTRALB | |
| SCHEMBL3176865 | 0.81 | KIF11 (0.46) | EGLN2TRPV4KIF11CUL4ATSHR | |
| SCHEMBL29104000 | 0.80 | ALDH1A1 (0.41) | EGLN2MEN1KMT2AHTTTSHR | |
| SCHEMBL15173739 | 0.80 | HTT (0.40) | EGLN2TTRALBHTTADRB2 | |
| SCHEMBL16411008 | 0.78 | MAP2K1 (0.40) | HDAC1HDAC6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108947782-B | Bromofluoride multi-substituted benzaldehyde derivative and preparation method thereof | 上海罕道医药科技有限公司 | 2021-08-24 | — | — | CN | claimed |
| US-4883609-A | LIQUID CRYSTALS | SEIKO EPSON CORPORATION (JP) | 1989-11-28 | — | — | US | claimed |
| JP-3038572-A | — | — | None | — | — | JP | disclosed |
| WO-2026101423-A1 | PHOTOSWITCHABLE CHEMICAL INDUCED DIMERIZATION SYSTEMS FOR CONTROL OF CELLULAR ACTIVITIES WITH LIGHT | WU YAOWEN (SE) | 2026-05-15 | — | — | WO | disclosed |
| CN-115197131-B | Azo 2-aminonicotinic acid benzyl ester derivative and preparation method and application thereof | 华东理工大学 | 2024-12-03 | — | — | CN | disclosed |
| US-12071404-B2 | Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides | UCB PHARMA GMBH (DE) | 2024-08-27 | — | — | US | disclosed |
| EP-3822274-B1 | SYNTHETIC INTERMEDIATES USEFUL FOR PREPARING SUBSTITUTED AMINOPURINE COMPOUNDS | SIGNAL PHARM LLC (US) | 2024-03-06 | — | — | EP | disclosed |
| US-11820746-B2 | Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides | UCB PHARMA GMBH (DE) | 2023-11-21 | — | — | US | disclosed |
| US-20230348384-A1 | Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides | UCB PHARMA GMBH (DE) | 2023-11-02 | — | — | US | disclosed |
| US-20230158035-A1 | SUBSTITUTED AMINOPURINE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARM LLC (US) | 2023-05-25 | — | — | US | disclosed |
| US-20230150998-A1 | COMPOUNDS AS GLP-1R AGONISTS | Terns, Inc. | 2023-05-18 | — | — | US | disclosed |
| US-5030382-A | Liquid crystals | SEIKO EPSON CORPORATION (JP) | 1991-07-09 | — | — | US | disclosed |
| JP-H0338572-A | PYRIMIDINE DERIVATIVE | SEIKO EPSON CORP | 1991-02-19 | — | — | JP | disclosed |
| EP-0391591-A2 | Pyrimidine derivative and liquid crystal composition incorporating the same | SEIKO EPSON CORPORATION (JP) | 1990-10-10 | — | — | EP | disclosed |
| EP-0390329-A1 | Pyrimidine derivative | SEIKO EPSON CORPORATION (JP) | 1990-10-03 | — | — | EP | disclosed |
| US-4883609-A | LIQUID CRYSTALS | SEIKO EPSON CORPORATION (JP) | 1989-11-28 | — | — | US | disclosed |
| US-4873357-A | Trifluoro acetyl-cyano-aniline intermediates for dopamine-βhydroxylase inhibitors | SMITHKLINE BECKMAN CORPORATION (US) | 1989-10-10 | — | — | US | disclosed |
| EP-0317175-A2 | Pyrimidine derivatives | SEIKO EPSON CORPORATION (JP) | 1989-05-24 | — | — | EP | disclosed |
| US-4719223-A | ENZYME INHIBITORS, HYPOTENSIVE, CARDIOTONIC DIURETIC | SMITHKLINE BECKMAN CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| EP-0221778-A2 | Dopamine-beta-hydroxylase inhibitors | SMITHKLINE BECKMAN CORPORATION (US) | 1987-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820746-B2 | Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides | GPR17, GPR18, GPR27 | EGLN2 1702/4885KHK 4362/4885TRPV4 285/4885 |
| US-20230348384-A1 | Aza (Indole)-, Benzothiophene-, And Benzofuran-3-Sulfonamides | GPR17, GPR18, GPR27 | EGLN2 1702/4885KHK 4362/4885TRPV4 285/4885 |
| US-20230158035-A1 | SUBSTITUTED AMINOPURINE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | TPMT, MGMT, TYMP | EGLN2 1255/4885KHK 2906/4885TRPV4 4861/4885 |
| US-12071404-B2 | Aza (indole)-, benzothiophene-, and benzofuran-3-sulfonamides | GPR17, GPR18, GPR27 | EGLN2 1702/4885KHK 4362/4885TRPV4 285/4885 |
| US-20230150998-A1 | COMPOUNDS AS GLP-1R AGONISTS | GLP1R, GIPR, GCGR | EGLN2 1804/4885KHK 1877/4885TRPV4 703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.