SCHEMBL25409493

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL25657020	0.78	AHR (0.47)	AHRMAOASMN1; SMN2KDM4EALDH1A1
	SCHEMBL24664985	0.77	CDC14B (0.44)	MAOASMN1; SMN2KDM4EALDH1A1MAPT
	SCHEMBL23830146	0.76	AHR (0.41)	AHRMAOASMN1; SMN2KDM4EALDH1A1
	SCHEMBL7126109	0.76	AHR (0.52)	AHRMAOASMN1; SMN2KDM4EALDH1A1
	SCHEMBL29271173	0.74	AHR (0.50)	AHRMAOASMN1; SMN2KDM4EALDH1A1
	SCHEMBL29271174	0.74	AHR (0.50)	AHRMAOASMN1; SMN2KDM4EALDH1A1
	SCHEMBL23883399	0.73	AHR (0.42)	AHRMAOASMN1; SMN2TTR
	SCHEMBL18338954	0.73	AHR (0.42)	AHRMAOASMN1; SMN2KDM4EALDH1A1
	SCHEMBL25408043	0.73	AHR (0.42)	AHRMAOASMN1; SMN2TTR
	SCHEMBL22725170	0.73	KDM4E (0.48)	AHRMAOASMN1; SMN2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.