Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69204 | 0.79 | — | — | |
| SCHEMBL22290833 | 0.74 | GABRG2 (0.41) | — | |
| SCHEMBL179565 | 0.74 | CYP1A2 (0.50) | MAPK1 | |
| SCHEMBL3015836 | 0.71 | ALDH1A1 (0.44) | — | |
| SCHEMBL5752399 | 0.71 | — | — | |
| SCHEMBL22134230 | 0.70 | — | — | |
| SCHEMBL27896166 | 0.69 | HCAR2 (0.37) | — | |
| SCHEMBL3008544 | 0.69 | LMNA (0.54) | MAPK1 | |
| SCHEMBL8646072 | 0.69 | SOAT1 (0.44) | MAPK1 | |
| SCHEMBL9425655 | 0.69 | LMNA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023169226-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS AS PARP INHIBITORS AND THE USE THEREOF | Impact Therapeutics (Shanghai), Inc (CN) | 2023-09-14 | — | — | WO | disclosed |