Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186168 | 0.72 | HCAR2 (0.52) | HCAR2KDM4E | |
| SCHEMBL3434664 | 0.72 | HCAR2 (0.47) | HCAR2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL27736514 | 0.71 | KMT2A (0.48) | HCAR2KDM4EALDH1A1 | |
| SCHEMBL27896037 | 0.71 | KDM4E (0.37) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL69204 | 0.70 | — | — | |
| SCHEMBL25410146 | 0.69 | MAPK1 (0.30) | — | |
| SCHEMBL179565 | 0.69 | CYP1A2 (0.50) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL28112074 | 0.68 | HCAR2 (0.43) | HCAR2 | |
| SCHEMBL27896024 | 0.67 | — | — | |
| SCHEMBL22290833 | 0.66 | GABRG2 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103003262-A | Nitrogenated aromatic heterocyclic ring derivative | KYOWA HAKKO KIRIN CO LTD | 2013-03-27 | — | — | CN | disclosed |