Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 5/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | FPR3 | P25089 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17650869 | 0.90 | PLG (0.36) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL26559935 | 0.90 | OPRM1 (0.36) | OPRM1OPRD1OPRK1SIRT1AVPR1A | |
| SCHEMBL17650868 | 0.88 | HDAC3 (0.32) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL17651521 | 0.87 | CA1 (0.41) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL18332122 | 0.82 | PLG (0.38) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL21695294 | 0.82 | HDAC3 (0.37) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL17813693 | 0.81 | RAB9A (0.36) | OPRM1OPRD1OPRK1SIRT1SIRT2 | |
| SCHEMBL22698653 | 0.81 | SIRT2 (0.36) | SIRT1SIRT2SIRT3 | |
| SCHEMBL16847844 | 0.80 | OPRM1 (0.33) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL17801960 | 0.80 | ITGB1 (0.34) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147329-A1 | ANTIBODY-CONJUGATED CHEMICAL INDUCERS OF DEGRADATION AND METHODS THEREOF | GENENTECH, INC. (US) | 2023-08-03 | — | — | WO | disclosed |