Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DUT | P33316 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | ENTPD2 | Q9Y5L3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25414625 | 0.79 | DHFR (0.39) | MEN1KMT2ADUTTDP1CYP3A4 | |
| SCHEMBL31614593 | 0.79 | DHFR (0.39) | MEN1KMT2ADUTTDP1CYP3A4 | |
| SCHEMBL15880881 | 0.69 | CYP3A4 (0.40) | MEN1KMT2ADUTTDP1CYP3A4 | |
| SCHEMBL25416162 | 0.68 | LMNA (0.39) | — | |
| SCHEMBL22589645 | 0.67 | MEN1 (0.37) | MEN1KMT2ADUTCYP3A4CYP2C9 | |
| SCHEMBL31614576 | 0.66 | DHFR (0.45) | — | |
| SCHEMBL18512754 | 0.65 | DUT (0.37) | MEN1KMT2ADUTCYP3A4CYP2C9 | |
| SCHEMBL21178129 | 0.63 | LMNA (0.44) | — | |
| SCHEMBL30404892 | 0.63 | POLG (0.37) | — | |
| SCHEMBL25752564 | 0.62 | DUT (0.51) | DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081105-A1 | CYCLIC PHOSPHORAMIDATE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2023-05-11 | — | — | WO | disclosed |