Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21858181 | 0.83 | DGAT1 (0.35) | DGAT1KLKB1NPC1 | |
| SCHEMBL31511396 | 0.83 | DGAT1 (0.34) | DGAT1NPC1 | |
| SCHEMBL26103766 | 0.83 | DGAT1 (0.41) | DGAT1NPC1 | |
| SCHEMBL31074609 | 0.81 | DGAT1 (0.34) | DGAT1KLKB1NPC1 | |
| SCHEMBL21350803 | 0.81 | DGAT1 (0.39) | DGAT1KLKB1NPC1 | |
| SCHEMBL28593694 | 0.81 | DGAT1 (0.35) | DGAT1KLKB1NPC1 | |
| SCHEMBL25413973 | 0.81 | DGAT1 (0.34) | DGAT1KLKB1NPC1 | |
| SCHEMBL26928849 | 0.78 | L3MBTL1 (0.37) | DGAT1KLKB1NPC1 | |
| SCHEMBL15726277 | 0.78 | NPC1 (0.37) | DGAT1NPC1 | |
| SCHEMBL29050026 | 0.77 | DGAT1 (0.32) | DGAT1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295123-A1 | NOVEL IMIDAZOLE-PYRAZOLE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-09-21 | — | — | US | disclosed |
| CN-116171280-A | Casein kinase 1 delta modulators | 詹森药业有限公司 | 2023-05-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295123-A1 | NOVEL IMIDAZOLE-PYRAZOLE DERIVATIVES | CYP3A7, NISCH, ARG1 | DGAT1 4877/4885KLKB1 2502/4885NPC1 1034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.