SCHEMBL2541892

SCHEMBL2541892

Cc1ccc(N=Nc2ccccc2C(=O)O)c(N)c1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 11/20 0.57
KMT2A Q03164 11/20 0.57
MAPT P10636 7/20 0.57
NPSR1 Q6W5P4 3/20 0.57
GAA P10253 2/20 0.57
TDP1 Q9NUW8 2/20 0.57
PSMD14 O00487 1/20 0.57
HSP90AA1 P07900 1/20 0.57
MMP2 P08253 1/20 0.57
THRB P10828 1/20 0.57
MAPK1 P28482 1/20 0.57
IDE P14735 1/20 0.49
CCNE2 O96020 1/20 0.48
CCNE1 P24864 1/20 0.48
CDK2 P24941 1/20 0.48
MYC P01106 2/20 0.48
POLB P06746 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2207266 0.83 KMT2A (0.67) MEN1KMT2AMAPTNPSR1GAA
SCHEMBL2207271 0.83 KMT2A (0.67) MEN1KMT2AMAPTNPSR1GAA
SCHEMBL28865978 0.80 MEN1 (0.58) MEN1KMT2AMAPTNPSR1GAA
SCHEMBL68503 0.78 IDE (0.71) MEN1KMT2AMAPTNPSR1GAA
SCHEMBL68504 0.78 IDE (0.71) MEN1KMT2AMAPTNPSR1GAA
SCHEMBL6345168 0.77 MAPT (0.49) MEN1KMT2AMAPTNPSR1TDP1
SCHEMBL29692284 0.77 MAPT (0.49) MEN1KMT2AMAPTNPSR1TDP1
SCHEMBL30530980 0.76 TRPA1 (0.50) MEN1KMT2AMAPTGAATDP1
Formic Acid SCHEMBL28018206 0.76 MAPT (0.41) MEN1KMT2AMAPTTDP1MAPK1
SCHEMBL731614 0.76 TRPA1 (0.50) MEN1KMT2AMAPTGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103890191-B Single cell whole genome amplification method 哈佛大学校长及研究员协会 2018-12-04 CN disclosed
US-9938586-B2 Methods for genetic analysis of textiles made of Gossypium barbadense and Gossypium hirsutum cotton APDN (B.V.I.) INC. (VG) 2018-04-10 US disclosed
US-20140295423-A1 METHODS FOR GENETIC ANALYSIS OF TEXTILES MADE OF GOSSYPIUM BARBADENSE AND GOSSYPIUM HIRSUTUM COTTON APDN (B.V.I.) INC. (VG) 2014-10-02 US disclosed
US-8669079-B2 Methods for genetic analysis of textiles made of Gossypium barbadense and Gossypium hirsutum cotton CARA THERAPEUTICS, INC. (US) 2014-03-11 US disclosed
US-20110250594-A1 METHODS FOR GENETIC ANALYSIS OF TEXTILES MADE OF GOSSYPIUM BARBADENSE AND GOSSYPIUM HIRSUTUM COTTON APDN (B.V.I.) INC. (VG) 2011-10-13 US disclosed
WO-2010056642-A2 METHODS FOR GENETIC ANALYSIS OF TEXTILES MADE OF GOSSYPIUM BARBADENSE AND GOSSYPIUM HIRSUTUM COTTON APPLIED DNA SCIENCES, INC. (US) 2010-05-20 WO disclosed