Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.38 |
| ▸ | KIT | P10721 | 2/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 3/20 | 0.34 |
| ▸ | CDK4 | P11802 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | CCNK | O75909 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25124396 | 0.75 | BRAF (0.42) | KITDDR1BRAF | |
| SCHEMBL21646384 | 0.72 | KIT (0.40) | PDE4BPDE4DKITDDR1BRAF | |
| SCHEMBL25239960 | 0.71 | KIT (0.46) | KITDDR1BRAF | |
| SCHEMBL25426296 | 0.70 | CSNK2B (0.32) | IRAK4CDK2CCNKCCNA2CDK12 | |
| SCHEMBL25777153 | 0.70 | KDM4E (0.38) | PDE4BIRAK4MAPK1CDK2CCNK | |
| SCHEMBL25087595 | 0.68 | ALDH1A1 (0.49) | KITDDR1 | |
| SCHEMBL15019947 | 0.66 | KIT (0.37) | PDE4BPDE4DKITDDR1BRAF | |
| SCHEMBL16478046 | 0.66 | DGAT1 (0.37) | PDE4BPDE4DKITDDR1MAPK9 | |
| SCHEMBL9729655 | 0.66 | KIT (0.38) | PDE4BPDE4DKITDDR1 | |
| SCHEMBL23545919 | 0.66 | KIT (0.36) | PDE4BPDE4DKITDDR1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250059194-A1 | ULK1 AND ULK2 INHIBITORS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2025-02-20 | — | — | US | disclosed |
| WO-2023122756-A2 | ULK1 AND ULK2 INHIBITORS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023122756-A2 | ULK1 AND ULK2 INHIBITORS | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2023-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250059194-A1 | ULK1 AND ULK2 INHIBITORS | ULK1, ULK2, ULK3 | PDE4B 4011/4885PDE4D 4461/4885MAPKAPK2 94/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.