⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27799993 | 0.78 | — | — | |
| SCHEMBL249390 | 0.78 | MEN1 (0.48) | — | |
| SCHEMBL3435521 | 0.78 | MEN1 (0.48) | — | |
| SCHEMBL3435870 | 0.78 | MEN1 (0.48) | — | |
| SCHEMBL15810269 | 0.78 | FAAH (0.39) | — | |
| SCHEMBL6023367 | 0.75 | TSHR (0.44) | — | |
| SCHEMBL249258 | 0.74 | SCN5A (0.47) | — | |
| SCHEMBL249257 | 0.74 | SCN5A (0.47) | — | |
| SCHEMBL560467 | 0.74 | MEN1 (0.51) | — | |
| SCHEMBL10033208 | 0.74 | MEN1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2810927-A1 | Therapeutic compounds | Sowood Healthcare LLC (US) | 2014-12-10 | — | — | EP | disclosed |
| US-8871815-B2 | Therapeutic compounds | SIGNATURE THERAPEUTICS, INC. (US) | 2014-10-28 | — | — | US | disclosed |
| US-20140206773-A1 | Therapeutic Compounds | SIGNATURE THERAPEUTICS, INC. (US) | 2014-07-24 | — | — | US | disclosed |
| US-8575400-B2 | Therapeutic compounds | SIGNATURE THERAPEUTICS, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| US-20130217783-A1 | Therapeutic Compounds | SIGNATURE THERAPEUTICS, INC. (US) | 2013-08-22 | — | — | US | disclosed |
| US-20130059919-A1 | Therapeutic Compounds | SOWOOD HEALTHCARE LLC | 2013-03-07 | — | — | US | disclosed |
| US-8350097-B2 | Therapeutic compounds | SIGNATURE THERAPEUTICS, INC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-8242315-B2 | Stereoisomers propofol therapeutic compounds | Singature Therapeutics, Inc. (US) | 2012-08-14 | — | — | US | disclosed |
| US-20120196939-A1 | Therapeutic Compounds | SOWOOD HEALTHCARE LLC | 2012-08-02 | — | — | US | disclosed |
| US-8173849-B2 | Therapeutic compounds | SIGNATURE THERAPEUTICS, INC. (US) | 2012-05-08 | — | — | US | disclosed |
| EP-2152651-B1 | THERAPEUTIC COMPOUNDS | PHARMACOFORE INC (US) | 2012-01-04 | — | — | EP | disclosed |
| EP-2392559-A1 | Therapeutic compounds | Pharmacofore, Inc. (US) | 2011-12-07 | — | — | EP | disclosed |
| US-8071818-B2 | Therapeutic compounds | PHARMACOFORE, INC. (US) | 2011-12-06 | — | — | US | disclosed |
| EP-2301908-A1 | (-)-stereoisomer of 2,6-di-sec-butylphenol and analogs thereof for promoting antiemetic effect and treatment of nausea and vomiting | Pharmacofore, Inc. (US) | 2011-03-30 | — | — | EP | disclosed |
| EP-2292577-A1 | (+)-stereoisomer of 2,6-di-sec-butylphenol and analogs thereof | Pharmacofore, Inc. (US) | 2011-03-09 | — | — | EP | disclosed |
| US-20100292346-A1 | Stereoisomers Propofol Therapeutic Compounds | SOWOOD HEALTHCARE LLC | 2010-11-18 | — | — | US | disclosed |
| EP-2146946-B1 | (-)- stereoisomer of 2,6-di-sec-butylphenol and analogs thereof | PHARMACOFORE INC (US) | 2010-11-10 | — | — | EP | disclosed |
| US-20100249246-A1 | Therapeutic Compounds | PHARMACOFORE, INC. (US) | 2010-09-30 | — | — | US | disclosed |
| EP-2146946-A2 | STEREOISOMERIC PROPOFOL THERAPEUTIC COMPOUNDS | Pharmacofore, Inc. (US) | 2010-01-27 | — | — | EP | disclosed |
| WO-2008141097-A2 | STEREOISOMERS PROPOFOL THERAPEUTIC COMPOUNDS | PHARMACOFORE, INC. (US) | 2008-11-20 | — | — | WO | disclosed |